Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | LHCGR | P22888 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14989181 | 0.90 | FAAH (0.51) | FAAHEPHX1ALDH1A1RAB9ABCHE | |
| SCHEMBL5095607 | 0.81 | FAAH (0.46) | FAAHEPHX1ALDH1A1RAB9A | |
| SCHEMBL5025385 | 0.81 | FAAH (0.46) | FAAHEPHX1ALDH1A1RAB9A | |
| SCHEMBL5138795 | 0.79 | FAAH (0.46) | FAAHEPHX1ALDH1A1RAB9ALHCGR | |
| SCHEMBL3389865 | 0.74 | SMYD3 (0.58) | ALDH1A1 | |
| SCHEMBL3393775 | 0.74 | SMYD3 (0.58) | ALDH1A1 | |
| SCHEMBL1690685 | 0.70 | FAAH (1.00) | FAAHEPHX1ALDH1A1RAB9ALHCGR | |
| SCHEMBL2078292 | 0.69 | SMYD3 (0.61) | ALDH1A1RAB9A | |
| SCHEMBL5025541 | 0.69 | MTNR1A (0.45) | FAAHEPHX1ALDH1A1RAB9ALHCGR | |
| SCHEMBL5025527 | 0.69 | CNR1 (0.48) | FAAHEPHX1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362027-B1 | ACYLATED 6,7,8,9-TETRAHYDRO-5H-BENZOCYCLOHEPTENYL AMINES AND THEIR USE AS PHARMACEUTICAL | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-05-21 | — | — | EP | claimed |