Sugi Predict

Sugi Predict / Compounds / SCHEMBL5026236

SCHEMBL5026236

SCHEMBL5026236

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PDE4A P27815 1/20 0.42
▸ LMNA P02545 2/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ TDP1 Q9NUW8 1/20 0.38
▸ MAPT P10636 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.32
▸ TSHR P16473 2/20 0.32
▸ AKR1C3 P42330 1/20 0.32
▸ USP2 O75604 1/20 0.32
▸ SLCO1B1 Q9Y6L6 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ AKR1C1 Q04828 1/20 0.32
▸ ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448867 1.00 PDE4A (0.42) PDE4ALMNAL3MBTL1TDP1MAPT
Mannitol SCHEMBL27796662 1.00 PDE4A (0.42) PDE4ALMNAL3MBTL1TDP1MAPT
Benzene SCHEMBL28171160 1.00 PDE4A (0.42) PDE4ALMNAL3MBTL1TDP1MAPT
SCHEMBL20945396 1.00 PDE4A (0.42) PDE4ALMNAL3MBTL1TDP1MAPT
SCHEMBL8720825 0.95 LMNA (0.36) PDE4ALMNAL3MBTL1TDP1MAPT
SCHEMBL27461489 0.95 LMNA (0.36) PDE4ALMNAL3MBTL1TDP1MAPT
SCHEMBL921741 0.95 LMNA (0.36) PDE4ALMNAL3MBTL1TDP1MAPT
Tert-Butylamine SCHEMBL28106851 0.91 CYP2C19 (0.36) PDE4ALMNAL3MBTL1TDP1MAPT
SCHEMBL27885025 0.90 TP53 (0.41) PDE4ALMNAL3MBTL1TDP1MAPT
Fructose SCHEMBL28207215 0.88 PDE4A (0.41) PDE4ALMNAL3MBTL1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250236633-A1 SYNTHESIS OF ISOMERICALLY PURE POLYOL-BASED PHOSPHORAMIDITES Roche Sequencing Solutions, Inc. (US) 2025-07-24 — — US disclosed
EP-4499655-A1 SYNTHESIS OF ISOMERICALLY PURE POLYOL-BASED PHOSPHORAMIDITES F. Hoffmann-La Roche AG (CH) 2025-02-05 — — EP disclosed
WO-2023186842-A1 SYNTHESIS OF ISOMERICALLY PURE POLYOL-BASED PHOSPHORAMIDITES F. HOFFMANN-LA ROCHE AG (CH) 2023-10-05 — — WO disclosed
EP-1999124-A1 GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME SIMON FRASER UNIVERSITY (CA) 2008-12-10 — — EP disclosed
WO-2007098597-A1 GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME SIMON FRASER UNIVERSITY (CA) 2007-09-07 — — WO disclosed
WO-1998007653-A1 CHIRAL HYDRIDE COMPLEXES ZEELAND CHEMICALS, INC. (US) 1998-02-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250236633-A1 SYNTHESIS OF ISOMERICALLY PURE POLYOL-BASED PHOSPHORAMIDITES PARG, PPA1, PGM2 PDE4A 3229/4885LMNA 2269/4885L3MBTL1 1210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.