Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16147772 | 1.00 | CYP3A4 (0.32) | CYP3A4HTTSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL9232886 | 0.85 | SMYD2 (0.34) | CYP3A4HTTSMN1; SMN2SLC6A4SLC6A3 | |
| SCHEMBL15219237 | 0.85 | SMYD2 (0.34) | CYP3A4HTTSMN1; SMN2SLC6A4SLC6A3 | |
| SCHEMBL19513655 | 0.81 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL705925 | 0.81 | RIPK1 (0.34) | CYP3A4HTTSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL8132885 | 0.79 | SLC6A2 (0.34) | CYP3A4HTTSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL30335514 | 0.79 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3RIPK1ATM | |
| SCHEMBL7354376 | 0.78 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL17491817 | 0.78 | ALDH1A1 (0.38) | SLC6A2SLC6A4SLC6A3RIPK1 | |
| SCHEMBL28549734 | 0.78 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939191-A1 | Furan derivatives, method of synthesis and uses thereof | Neuropharma S.A. (ES) | 2008-07-02 | — | — | EP | disclosed |