Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA4 | P22748 | 2/20 | 0.60 |
| ▸ | CA6 | P23280 | 2/20 | 0.60 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16467867 | 0.82 | CA1 (0.56) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL9281702 | 0.82 | CA1 (0.56) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL10849987 | 0.79 | CA1 (0.52) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL2475835 | 0.77 | CA1 (0.68) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL38660050 | 0.77 | CA1 (0.68) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL20414679 | 0.77 | CA1 (0.50) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL28859539 | 0.76 | CA1 (0.53) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL29750 | 0.75 | CA1 (0.65) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL30630011 | 0.75 | CA2 (1.00) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL344271 | 0.75 | CA2 (1.00) | CA1CA2CA4CA6PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076821-A2 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-04-22 | — | — | WO | disclosed |
| EP-1937683-A1 | METHOD FOR 1H-IMIDAZOÝ4,5-c¨PYRIDINES AND ANALOGS THEREOF | Coley Pharmaceutical Group, Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007035935-A1 | METHOD FOR 1H-IMIDAZO[4,5-c]PYRIDINES AND ANALOGS THEREOF | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-03-29 | — | — | WO | disclosed |