Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA6 | P23280 | 2/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364060 | 0.78 | POLB (0.48) | CA1CA2CA9CA5APOLB | |
| SCHEMBL31148931 | 0.78 | POLB (0.48) | CA1CA2CA9CA5APOLB | |
| SCHEMBL7464033 | 0.76 | RBP4 (0.44) | CA1CA2CA9CA5AMAPT | |
| SCHEMBL5026645 | 0.76 | CA1 (0.60) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL27560569 | 0.75 | CA1 (0.55) | CA1CA2CA9LOXKMT2A | |
| SCHEMBL27561927 | 0.75 | CTSB (0.42) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL11226379 | 0.74 | PLCG1 (0.60) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL4436494 | 0.74 | SMN1; SMN2 (0.46) | CA1CA2CA4CA6CA9 | |
| Ammonia Solution, Strong SCHEMBL27568563 | 0.74 | CA1 (0.53) | CA1CA2CA9LOXKMT2A | |
| SCHEMBL28592429 | 0.73 | F2 (0.56) | CA1CA2POLBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-105130855-B | Succinylated hydroxy amine derivatives and application thereof | 约翰斯霍普金斯大学 | 2018-05-25 | — | — | CN | disclosed |