Sugi Predict

Sugi Predict / Compounds / Hydrazine

Hydrazine

Hydrazine

SCHEMBL5026845

Cc1nc(C)c(N=O)c(C)n1.NN

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CDK2 P24941 2/20 0.33
▸ CCNA2 P20248 1/20 0.33
▸ CCNA1 P78396 1/20 0.33
▸ CDK1 P06493 1/20 0.31
▸ CDK4 P11802 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14490774 0.83 CDK2 (0.42) CDK2CCNA2CCNA1CDK1CDK4
SCHEMBL8864824 0.68 ALDH1A1 (0.33) —
SCHEMBL13802550 0.66 CDK2 (0.40) CDK2CCNA2CCNA1CDK1CDK4
SCHEMBL21076650 0.66 CDK2 (0.40) CDK2CCNA2CCNA1CDK1CDK4
SCHEMBL6402248 0.66 CDK2 (0.40) CDK2CCNA2CCNA1CDK1CDK4
SCHEMBL13752394 0.65 CCNA2 (0.53) CDK2CCNA2CCNA1
SCHEMBL30592426 0.65 MAPT (0.33) HTTKMT2A
SCHEMBL12652113 0.64 CDK1 (0.66) CDK2CDK1CDK4KMT2A
SCHEMBL15177939 0.64 — —
SCHEMBL8382893 0.64 ALDH1A1 (0.30) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2008210-A1 MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE CSIR (ZA) 2008-12-31 — — EP disclosed
WO-2007105023-A1 MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE CSIR (ZA) 2007-09-20 — — WO disclosed