Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14490772 | 0.84 | CDK2 (0.47) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL8864824 | 0.84 | ALDH1A1 (0.33) | — | |
| SCHEMBL29473573 | 0.78 | CDK2 (0.52) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL29693584 | 0.78 | CDK2 (0.41) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL4160357 | 0.78 | CDK2 (0.52) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL2745214 | 0.78 | CDK2 (0.41) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL14490774 | 0.78 | CDK2 (0.42) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL10441417 | 0.75 | CDK2 (0.38) | CDK2CCNA2CCNA1CDK1CDK4 | |
| Nitrous Acid SCHEMBL29168822 | 0.75 | CDK2 (0.48) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL5026853 | 0.75 | CDK2 (0.38) | CDK2CCNA2CCNA1CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001089587-A2 | AGENTS FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-11-29 | — | — | WO | claimed |
| US-9573952-B2 | Methods of preparing toll-like receptor modulators | GILEAD SCIENCES, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-9573952-B2 | Methods of preparing toll-like receptor modulators | GILEAD SCIENCES, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-20160075707-A1 | METHODS OF PREPARING TOLL-LIKE RECEPTOR MODULATORS | GILEAD SCIENCES, INC. | 2016-03-17 | — | — | US | disclosed |
| US-20050153978-A1 | Medicaments | GLAXO GROUP LIMITED (GB) | 2005-07-14 | — | — | US | disclosed |
| EP-1487441-A2 | BENZIMIDAZOLES AND THEIR USE AS MITOGEN-ACTIVATED- AND RHO-KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080125-A2 | BENZIMIDAZOLES AND THEIR USE AS MITOGEN-ACTIVATED- AND RHO-KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | disclosed |
| WO-2001089587-A2 | AGENTS FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075707-A1 | METHODS OF PREPARING TOLL-LIKE RECEPTOR MODULATORS | TLR3, TLR4, TLR6 | CDK2 3623/4885CCNA2 4759/4885CCNA1 4823/4885 |
| US-20050153978-A1 | Medicaments | GRK1, ROCK1, GRK7 | CDK2 1802/4885CCNA2 3332/4885CCNA1 1408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.