Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28158644 | 0.81 | DNM2 (0.45) | CYP2D6CYP2C19EGFRMEN1KMT2A | |
| SCHEMBL9181933 | 0.78 | DNM2 (0.54) | EGFRMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL17728852 | 0.78 | DNM2 (0.57) | EGFRNPC1KDM4EPOLBMAPT | |
| SCHEMBL29402899 | 0.77 | EGFR (0.51) | CYP2D6CYP2C19EGFRNPSR1MAP4K4 | |
| SCHEMBL16840824 | 0.77 | EGFR (0.55) | CYP2D6CYP2C19EGFRMEN1KMT2A | |
| SCHEMBL11981509 | 0.77 | EGFR (0.55) | CYP2D6CYP2C19EGFRMEN1KMT2A | |
| SCHEMBL807297 | 0.77 | EGFR (0.51) | CYP2D6CYP2C19EGFRNPSR1MAP4K4 | |
| SCHEMBL19489281 | 0.77 | EGFR (0.48) | CYP2D6CYP2C19EGFRMEN1KMT2A | |
| SCHEMBL16656099 | 0.77 | CYP1A2 (0.54) | CYP2D6CYP2C19MEN1KMT2ANPC1 | |
| SCHEMBL20081779 | 0.77 | HRH3 (0.44) | CYP2D6CYP2C19EGFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-2339351-A1 | Non-peptide agonists and antagonists of adrenomedullin and gastrin releasing peptide | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (US) | 2011-06-29 | — | — | EP | disclosed |
| CN-101438288-A | Regulation of phosphoryl transferase activity of glutamine synthetase | CSIR CORP (ZA) | 2009-05-20 | — | — | CN | disclosed |
| EP-2008210-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |
| EP-0004173-B1 | 2,3-DIHYDROIMIDAZO (1,2-C) PYRIMIDINES, THEIR PREPARATION, FORMULATIONS CONTAINING THEM AND THEIR USE AS PHARMACEUTICALS | ELI LILLY AND COMPANY (US) | 1982-09-22 | — | — | EP | disclosed |
| EP-0004173-A1 | 2,3-Dihydroimidazo (1,2-c) pyrimidines, their preparation, formulations containing them and their use as pharmaceuticals | ELI LILLY AND COMPANY (US) | 1979-09-19 | — | — | EP | disclosed |
| US-4153695-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1979-05-08 | — | — | US | disclosed |