Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028967 | 0.91 | ALDH1A1 (0.49) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5031707 | 0.85 | ALDH1A1 (0.44) | MAPK1GAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4398352 | 0.81 | ALDH1A1 (0.43) | MAPK1GAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4398354 | 0.81 | ALDH1A1 (0.43) | MAPK1GAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4394289 | 0.80 | NPC1 (0.49) | MAPK1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4400060 | 0.80 | NPC1 (0.49) | MAPK1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4398265 | 0.79 | NPC1 (0.55) | MAPK1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4398428 | 0.79 | NPC1 (0.55) | MAPK1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5028982 | 0.78 | ALDH1A1 (0.47) | GAASMN1; SMN2ALDH1A1POLBTDP1 | |
| SCHEMBL5444750 | 0.72 | MAPK1 (0.67) | MAPK1SMN1; SMN2MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007393-A2 | THIAZOLE AND THIOPHENE ANALOGUES, AND THEIR USE IN TREATING AUTOIMMUNE DISEASES AND CANCERS | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College (US) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118149-A2 | THIAZOLE AND THIOPHENE ANALOGUES, AND THEIR USE IN TREATING AUTOIMMUNE DISEASES AND CANCERS | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL LOLLEGE (US) | 2007-10-18 | — | — | WO | disclosed |