Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 2/20 | 0.33 |
| ▸ | ARG2 | P78540 | 2/20 | 0.33 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016090 | 1.00 | ODC1 (0.42) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL2270879 | 1.00 | ODC1 (0.42) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL4617700 | 0.95 | ODC1 (0.37) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL4617707 | 0.95 | ODC1 (0.37) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL28914719 | 0.95 | ODC1 (0.37) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL3294151 | 0.91 | DGAT1 (0.38) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL1066048 | 0.89 | DGAT1 (0.41) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL7705520 | 0.89 | DGAT1 (0.41) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL6429484 | 0.86 | TDP1 (0.42) | DGAT1ARG1ARG2GGT1KMT2A | |
| SCHEMBL345584 | 0.86 | FDPS (0.36) | DGAT1ARG1ARG2GGT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598123-B2 | Peptide analogues | PFIZER INC. (US) | 2013-12-03 | — | — | US | disclosed |
| US-20120329724-A1 | PEPTIDE ANALOGUES | PFIZER LIMITED | 2012-12-27 | — | — | US | disclosed |
| US-20110207654-A1 | PEPTIDE ANALOGUES | PFIZER INC. | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329724-A1 | PEPTIDE ANALOGUES | OPRL1, OGFR, OPRM1 | ODC1 2286/4885LMNA 4556/4885BLM 4806/4885 |
| US-20110207654-A1 | PEPTIDE ANALOGUES | OPRL1, OGFR, OPRM1 | ODC1 2286/4885LMNA 4556/4885BLM 4806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.