SCHEMBL5027487

SCHEMBL5027487

COc1ccc(O[SiH3])c(OC)c1OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.41
CYP1B1 Q16678 1/20 0.41
AOC3 Q16853 1/20 0.41
MAPT P10636 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 2/20 0.40
CYP19A1 P11511 2/20 0.40
POLB P06746 2/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.39
NQO2 P16083 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674074 0.86 CA9 (0.50) CYP1A1CYP1B1AOC3MAPTTDP1
SCHEMBL30701949 0.86 CA9 (0.50) CYP1A1CYP1B1AOC3MAPTTDP1
SCHEMBL7058917 0.85 SMN1; SMN2 (0.50) CYP1A1CYP1B1MAPTALDH1A1CYP19A1
SCHEMBL28322511 0.78 CYP1A1 (0.44) CYP1A1CYP1B1AOC3MAPTTDP1
SCHEMBL308029 0.77 MAPT (0.43) CYP1A1CYP1B1AOC3MAPTTDP1
SCHEMBL642228 0.76 HDAC4 (0.58) MAPTALDH1A1KDM4EHPGDHDAC4
SCHEMBL1402402 0.74 MAPT (0.42) CYP1A1CYP1B1AOC3MAPTTDP1
SCHEMBL1226775 0.74 ALDH1A1 (0.46) CYP1A1CYP1B1AOC3MAPTTDP1
SCHEMBL29767819 0.74 ALDH1A1 (0.46) CYP1A1CYP1B1AOC3MAPTTDP1
SCHEMBL4635687 0.74 AOC3 (0.41) CYP1A1CYP1B1AOC3MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106632744-B Propylene polymerization catalyst, preparation method and application 北京化工大学 2020-05-15 CN disclosed
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 EP disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 US disclosed
US-6824866-B1 Porous silica substrates for polymer synthesis and assays AFFYMETRIX, INC. 2004-11-30 US disclosed
US-20040092396-A1 Porous silica substrates for polymer synthesis and assays AFFYMETRIX, INC. 2004-05-13 US disclosed
EP-0754739-B1 Curable coating composition KANSAI PAINT CO LTD (JP) 2003-10-29 EP disclosed
WO-2000061282-A1 POROUS SILICA SUBSTRATES FOR POLYMERS SYNTHESIS AND ASSAYS AFFYMETRIX, INC. (US) 2000-10-19 WO disclosed
US-5684095-A POLYESTER, POLYEPOXIDE, SILICON COMPOUND AND CHELATE CMPOUND IN SOLVENT KANSAI PAINT COMPANY, LIMITED (JP) 1997-11-04 US disclosed
EP-0754739-A2 Curable coating composition KANSAI PAINT CO., LTD. (JP) 1997-01-22 EP disclosed
US-4810674-A STRENGTH AND OPTICAL TRANSPARENCY HOECHST CELANESE CORP. (US) 1989-03-07 US disclosed
EP-0283144-A1 Porous glass monoliths HOECHST CELANESE CORPORATION (US) 1988-09-21 EP disclosed
US-4765818-A HYDROLYZING TETRAALKOXYSILANES IN A SOL-GEL REACTION MEDIUM OF WATER AND TRIOXANE HOECHST CELANESE CORPORATION (US) 1988-08-23 US disclosed