SCHEMBL308029

SCHEMBL308029

COc1ccc([SiH3])c(OC)c1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
ALDH1A1 P00352 2/20 0.43
POLB P06746 2/20 0.43
KMT2A Q03164 1/20 0.43
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
CYP1A1 P04798 1/20 0.40
CYP1B1 Q16678 1/20 0.40
AOC3 Q16853 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
CYP19A1 P11511 1/20 0.39
NFE2L2 Q16236 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674074 0.84 CA9 (0.50) MAPTALDH1A1POLBKMT2ACYP1A1
SCHEMBL30701949 0.84 CA9 (0.50) MAPTALDH1A1POLBKMT2ACYP1A1
SCHEMBL22371477 0.81 KDM4E (0.42) MAPTALDH1A1KDM4E
SCHEMBL702177 0.78 SMN1; SMN2 (0.56) MAPTALDH1A1POLBKMT2ACYP1A1
SCHEMBL10388469 0.78 LTA4H (0.45) MAPTALDH1A1KMT2AKDM4ECA4
SCHEMBL5027487 0.77 CYP1A1 (0.41) MAPTALDH1A1POLBKMT2ACYP1A1
SCHEMBL28322511 0.76 CYP1A1 (0.44) MAPTALDH1A1POLBKMT2ACYP1A1
SCHEMBL9420335 0.75 ALDH1A1 (0.35) MAPTALDH1A1KMT2ATDP1KDM4E
SCHEMBL4241468 0.75 ACHE (0.41) MAPTALDH1A1POLBKMT2AKDM4E
SCHEMBL642228 0.74 HDAC4 (0.58) MAPTALDH1A1KDM4EHPGDHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1743 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080650-A Phase change heat conduction material based on block organosilicon copolymer and preparation method thereof 2026-05-26 CN claimed
US-12637616-B2 Etching solution for selectively removing silicon-germanium alloy from a silicon-germanium/ silicon stack during manufacture of a semiconductor device VERSUM MATERIALS US, LLC (US) 2026-05-26 US claimed
CN-122037138-A Modified epoxy resin, preparation method thereof, epoxy plastic package material and application 深圳先进电子材料国际创新研究院 2026-05-15 CN claimed
CN-122011243-A Chromium-based polyethylene catalyst for loop slurry polymerization process and preparation method thereof 淄博新塑化工有限公司 2026-05-12 CN claimed
US-20260117072-A1 COATING COMPOSITION AND ITS COATED MATERIAL PRODUCTS, KITS, AND METHODS OF USE MEGA P&C ADVANCED MAT SHANGHAI CO LTD (CN) 2026-04-30 US claimed
US-20260061735-A1 DEFORMATION-CONTROLLING FILM AND METHOD OF CONTROLLING DEFORMATION OF SHEET LU CIAN TONG (TW) 2026-03-05 US claimed
US-12521757-B2 Bilayer composition for surface treatment of steel plate and surface-treated steel plate using same POSCO CO., LTD (KR) 2026-01-13 US claimed
US-20260000623-A1 DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES CHAN, Hardy Wai Hong (TW) 2026-01-01 US claimed
EP-4653505-A1 COATING COMPOSITION, MATERIAL PRODUCT THEREOF, KIT, AND USE METHOD Mega P&C Advanced Materials (Shanghai) Co., Ltd. (CN) 2025-11-26 EP claimed
EP-4646391-A1 MESOPOROUS SILICA PARTICLES Luxembourg Institute of Science and Technology (LIST) (LU) 2025-11-12 EP claimed
US-20030069379-A1 Room temperature curing organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-04-10 US claimed
US-6479057-B2 USE OF AT LEAST ONE INORGANIC-ORGANIC HYBRID PREPOLYMER IN COSMETIC AGENTS TO PROVIDE LONG-LASTING HAIR SETTING WELLA AKTIENGESELLSCHAFT (DE) 2002-11-12 US claimed
US-6071663-A CARRIER CORE COATED WITH A SILICONE RESIN CONTAINING A CROSSLINKING AGENT HAVING A PHENYL GROUP; STABILITY POWDERTECH CO., LTD. (JP) 2000-06-06 US claimed
US-5407739-A Ignition resistant meltbrown or spunbonded insulation material THE DOW CHEMICAL COMPANY (US) 1995-04-18 US claimed
US-5399423-A Ignition resistant meltblown or spunbonded insulation material THE DOW CHEMICAL COMPANY (US) 1995-03-21 US claimed
WO-1995004181-A1 IGNITION RESISTANT MELTBLOWN OR SPUNBONDED INSULATION MATERIAL THE DOW CHEMICAL COMPANY (US) 1995-02-09 WO claimed
EP-0466774-A4 NONGRAPHITIC IGNITION RESISTANT STRUCTURES 1992-11-25 EP claimed
EP-0466774-A1 NONGRAPHITIC IGNITION RESISTANT STRUCTURES THE DOW CHEMICAL COMPANY (US) 1992-01-22 EP claimed
US-5024877-A Structure of non-graphitic carbonaceous material and an organosilicone polymer THE DOW CHEMICAL COMPANY (US) 1991-06-18 US claimed
WO-1990012686-A1 NONGRAPHITIC IGNITION RESISTANT STRUCTURES THE DOW CHEMICAL COMPANY (US) 1990-11-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637616-B2 Etching solution for selectively removing silicon-germanium alloy from a silicon-germanium/ silicon stack during manufacture of a semiconductor device KCNH3, F7, KCNH2 MAPT 3711/4885ALDH1A1 3530/4885POLB 883/4885
US-20260117072-A1 COATING COMPOSITION AND ITS COATED MATERIAL PRODUCTS, KITS, AND METHODS OF USE ILK, BMI1, C9 MAPT 2420/4885ALDH1A1 222/4885POLB 355/4885
US-20260061735-A1 DEFORMATION-CONTROLLING FILM AND METHOD OF CONTROLLING DEFORMATION OF SHEET FIP1L1, SNU13, PCBP1 MAPT 2912/4885ALDH1A1 4477/4885POLB 2680/4885
US-20260000623-A1 DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES AQP4, ABCB1, SRMS MAPT 915/4885ALDH1A1 2548/4885POLB 3373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.