SCHEMBL502750

SCHEMBL502750

CCCC(CCC)(CCCC(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.50
GPR84 Q9NQS5 7/20 0.48
PPARG P37231 7/20 0.48
PPARD Q03181 7/20 0.48
PPARA Q07869 7/20 0.48
HDAC11 Q96DB2 5/20 0.48
TSHR P16473 5/20 0.48
PTPN1 P18031 3/20 0.48
ALDH1A1 P00352 3/20 0.48
KMT2A Q03164 3/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
SLC22A6 Q4U2R8 2/20 0.48
MEN1 O00255 2/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
ESR1 P03372 1/20 0.48
ALOX15 P16050 1/20 0.48
PDE4A P27815 1/20 0.48
PDE3A Q14432 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18343637 0.94 AKR1B1 (0.45) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL11122205 0.94 AKR1B1 (0.54) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL2231185 0.92 AKR1B1 (0.46) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL4300910 0.92 GPR84 (0.56) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL27998363 0.92 GPR84 (0.56) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL31099576 0.92 GPR84 (0.56) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL20564579 0.92 GPR84 (0.56) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL2379348 0.92 GPR84 (0.56) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL126142 0.91 AKR1B1 (0.56) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL2141061 0.89 AKR1B1 (0.60) AKR1B1GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3252103-B1 POLYLACTIC ACID-CONTAINING AQUEOUS DISPERSION TOYO BOSEKI (JP) 2020-09-09 EP claimed
EP-3676358-A1 TRANSMISSION LUBRICANT COMPOSITION BASF SE (DE) 2020-07-08 EP claimed
EP-3507280-A2 COALESCING AGENT DERIVED FROM DIOXOLANE DERIVATIVES PTT Global Chemical Public Company Limited (TH) 2019-07-10 EP claimed
WO-2019046252-A1 TRANSMISSION LUBRICANT COMPOSITION BASF SE (DE) 2019-03-07 WO claimed
US-20190000746-A1 HAIR-STYLING COMPOSITIONS COMPRISING A COMBINATION OF LATEX FILM-FORMING POLYMERS L'OREAL (FR) 2019-01-03 US claimed
US-9144552-B2 Rapidly dissolving film for delivery of an active agent A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCES (RU) 2015-09-29 US claimed
EP-2841045-A1 HYDROPHILIC PRESSURE SENSITIVE BIOADHESIVES WITH TARGETED ADHESION TOWARDS TEETH AND TOOTH CARE COMPOSITIONS BASED THEREON Inpolya International SA (CH) 2015-03-04 EP claimed
US-20140147489-A1 RAPIDLY DISSOLVING FILM FOR DELIVERY OF AN ACTIVE AGENT A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCES (RU) 2014-05-29 US claimed
US-8658201-B2 Rapidly dissolving film for delivery of an active agent CORIUM INTERNATIONAL, INC. (US) 2014-02-25 US claimed
WO-2013162404-A1 HYDROPHILIC PRESSURE SENSITIVE BIOADHESIVES WITH TARGETED ADHESION TOWARDS TEETH AND TOOTH CARE COMPOSITIONS BASED THEREON FELDSTEIN MIKHAIL MAJOROVICH (RU) 2013-10-31 WO claimed
US-20050208110-A1 Rapidly dissolving film for delivery of an active agent CORIUM PHARMA SOLUTIONS, INC. 2005-09-22 US claimed
WO-2005074894-A1 RAPIDLY DISSOLVING FILM FOR DELIVERY OF AN ACTIVE AGENT CORIUM INTERNATIONAL (US) 2005-08-18 WO claimed
EP-0944310-B1 STABILIZED ASCORBYL COMPOSITIONS PERRICONE NICHOLAS V DR (US) 2005-04-06 EP claimed
EP-1390085-A1 HYDROGEL COMPOSITIONS A.V. Topchiev Institute of Petrochemical Synthesis (RU) 2004-02-25 EP claimed
US-20030170308-A1 Hydrophobic phase comprises (i) a hydrophobic polymer, (ii) a plasticizer, (iii) a tackifying resin, and (iv) an optional antioxidant; and a hydrophilic phase; wound dressings, transdermal drug delivery COLUMBUS INVESTMENT HOLDINGS SA (CH) 2003-09-11 US claimed
EP-1009366-B1 COSMETIC COMPOSITIONS COMPRISING A POLYOXYALKYLATED AMINATED SILICONE BLOCK POLYMER AND A CONDITIONING AGENT AND THEIR USE OREAL (FR) 2003-03-26 EP claimed
WO-2002087645-A1 HYDROGEL COMPOSITIONS A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS (RU) 2002-11-07 WO claimed
EP-0453483-B1 NON-TOXIC, NON-FLAMMABLE CLEANER FOR PRINTED BOARD CLEANING MARTIN MARIETTA CORP (US) 1996-02-28 EP claimed
US-4298411-A FOR MISSILES; GOOD MECHANICAL PROPERTIES HERCULES INCORPORATED (US) 1981-11-03 US claimed
US-3963545-A NITROCELLULOSE, NITROGLYCERIN, DIPROPYLADIPATE, 2-NITRODIPHENYLAMINE, CANDELILLA WAX, ALUMINUM THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-06-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190000746-A1 HAIR-STYLING COMPOSITIONS COMPRISING A COMBINATION OF LATEX FILM-FORMING POLYMERS PIK3C3, POLR1C, SHH AKR1B1 4533/4885GPR84 4577/4885PPARG 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.