Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552261 | 0.88 | TLR8 (0.36) | CYP1A2TLR8DHFRMCHR1TSHR | |
| SCHEMBL5552250 | 0.83 | CYP1A2 (0.39) | CYP1A2CYP2A6ALDH1A1CA1CA2 | |
| SCHEMBL5554342 | 0.79 | NOS2 (0.33) | ALDH1A1KDM4EMAPT | |
| SCHEMBL29022755 | 0.79 | HTR1B (0.35) | MAPK1ALDH1A1KDM4EHTR1BTSHR | |
| SCHEMBL106489 | 0.78 | TSHR (0.35) | TLR8ALDH1A1TSHRACHE | |
| SCHEMBL5140507 | 0.75 | TSHR (0.35) | CYP1A2MAPK1CYP2A6ALDH1A1KDM4E | |
| SCHEMBL5031063 | 0.73 | SCN4A (0.40) | CYP1A2CYP2A6ALDH1A1TSHR | |
| SCHEMBL974558 | 0.72 | KMT2A (0.33) | MAPK1TLR8DHFRALDH1A1KDM4E | |
| SCHEMBL13027881 | 0.72 | CYP1A2 (0.35) | CYP1A2CYP2A6 | |
| SCHEMBL29992586 | 0.72 | MAPK1 (0.35) | CYP1A2MAPK1CYP2A6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |