Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029870 | 0.88 | NOS2 (0.37) | NOS2NOS3NOS1KDM4EGAA | |
| SCHEMBL2478476 | 0.83 | NOS3 (0.33) | NOS2NOS3NOS1KDM4EALDH1A1 | |
| SCHEMBL5027520 | 0.79 | CYP1A2 (0.33) | KDM4EALDH1A1MAPT | |
| SCHEMBL3482484 | 0.77 | NOS3 (0.31) | NOS2NOS3NOS1 | |
| SCHEMBL5140507 | 0.75 | TSHR (0.35) | NOS2NOS1KDM4EALDH1A1LMNA | |
| SCHEMBL5029804 | 0.73 | NOS2 (0.37) | NOS2NOS3NOS1KDM4EALDH1A1 | |
| SCHEMBL3108980 | 0.70 | ACHE (0.39) | NOS2NOS3NOS1KDM4EALDH1A1 | |
| SCHEMBL3339303 | 0.70 | NLRP3 (0.33) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL13027164 | 0.69 | ACHE (0.41) | CRHR1 | |
| SCHEMBL106489 | 0.69 | TSHR (0.35) | ALDH1A1LMNAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |