Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16353820 | 0.90 | RAPGEF4 (0.31) | RAPGEF4 | |
| SCHEMBL12018763 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TSHRRAPGEF4TDP1FFAR4 | |
| SCHEMBL682063 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TSHRRAPGEF4TDP1FFAR4 | |
| SCHEMBL5030064 | 0.84 | TP53 (0.31) | RAPGEF4TDP1TP53 | |
| SCHEMBL12313701 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRRAPGEF4TDP1FFAR4 | |
| SCHEMBL12313699 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRRAPGEF4TDP1FFAR4 | |
| SCHEMBL12313728 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRRAPGEF4TDP1FFAR4 | |
| SCHEMBL12313740 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRRAPGEF4TDP1FFAR4 | |
| SCHEMBL13197770 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRRAPGEF4TDP1FFAR4 | |
| SCHEMBL12313715 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRRAPGEF4TDP1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080304867-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | RICOH COMPANY, LTD. | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080304867-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | KDM1A, C9, JMJD6 | ALDH1A1 1243/4885TSHR 4581/4885RAPGEF4 3290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.