Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027588 | 1.00 | ENPP2 (0.33) | ENPP2MAPK1 | |
| SCHEMBL5034288 | 0.89 | ENPP2 (0.38) | ENPP2MAPK1 | |
| SCHEMBL4149688 | 0.85 | SCN9A (0.32) | ENPP2MAPK1 | |
| SCHEMBL4149686 | 0.85 | SCN9A (0.32) | ENPP2MAPK1 | |
| SCHEMBL5032332 | 0.79 | KDM4E (0.40) | ENPP2 | |
| SCHEMBL5032336 | 0.79 | KDM4E (0.40) | ENPP2 | |
| SCHEMBL5034304 | 0.73 | AAK1 (0.43) | MAPK1 | |
| SCHEMBL4158790 | 0.73 | NFE2L2 (0.37) | — | |
| SCHEMBL4158795 | 0.73 | NFE2L2 (0.37) | — | |
| SCHEMBL4150603 | 0.72 | RXFP1 (0.35) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429609-B2 | Pyrazole compound and medicinal composition containing the same | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-09-30 | — | — | US | disclosed |
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-24 | — | — | US | disclosed |
| EP-1510516-A1 | PYRAZOLE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | CNKSR1, NR3C2, CSNK2B | ENPP2 3605/4885MAPK1 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.