SCHEMBL5028273

SCHEMBL5028273

c1ccc2c(c1)oc1c(-c3cccc4c3oc3c(-c5cccc6c5oc5ccccc56)cccc34)cccc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.66
PRKDC P78527 5/20 0.50
PIK3CD O00329 1/20 0.49
PIK3CB P42338 1/20 0.49
AHR P35869 3/20 0.46
GGPS1 O95749 1/20 0.44
ATM Q13315 1/20 0.44
MAOA P21397 2/20 0.44
KDM4E B2RXH2 3/20 0.43
MAPT P10636 3/20 0.43
HPGD P15428 3/20 0.43
CYP3A4 P08684 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ALDH1A1 P00352 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GLA P06280 1/20 0.43
PGAM1 P18669 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
HDAC8 Q9BY41 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10945864 0.98 ALOX5 (0.68) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL12996513 0.95 ALOX5 (0.66) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL431458 0.95 ALOX5 (0.66) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL430138 0.95 ALOX5 (0.66) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL17974232 0.93 ALOX5 (0.69) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL16633881 0.91 ALOX5 (0.67) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL21431853 0.90 ALOX5 (0.59) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL24171048 0.90 ALOX5 (0.68) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL22129979 0.89 ALOX5 (0.55) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL16553323 0.89 ALOX5 (0.55) ALOX5PRKDCPIK3CDPIK3CBAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020022779-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-01-30 WO disclosed
US-20190372022-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD (KR) 2019-12-05 US disclosed
EP-2453496-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, NOVEL COMPOUND, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta Holdings, Inc. (JP) 2012-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190372022-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD1, OCIAD2, AOX1 ALOX5 108/4885PRKDC 2971/4885PIK3CD 2191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.