Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35210071 | 0.98 | LMNA (0.37) | LMNAOPRM1TSHRTHRBTRPM8 | |
| SCHEMBL35210072 | 0.98 | LMNA (0.37) | LMNAOPRM1TSHRTHRBTRPM8 | |
| SCHEMBL35210073 | 0.98 | LMNA (0.37) | LMNAOPRM1TSHRTHRBTRPM8 | |
| SCHEMBL432262 | 0.93 | LMNA (0.31) | LMNA | |
| SCHEMBL430953 | 0.83 | — | — | |
| SCHEMBL35210070 | 0.78 | TSHR (0.33) | LMNATSHRTHRB | |
| SCHEMBL35210076 | 0.78 | TSHR (0.33) | LMNATSHRTHRB | |
| SCHEMBL6574221 | 0.77 | — | — | |
| SCHEMBL30778293 | 0.77 | — | — | |
| SCHEMBL27391119 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |