SCHEMBL5028501

SCHEMBL5028501

Cc1ccc(Nc2ccc(Nc3ccc(C)cc3C)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 3/20 0.61
GAA P10253 6/20 0.53
MEN1 O00255 6/20 0.53
KMT2A Q03164 6/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
G6PD P11413 1/20 0.53
HPGD P15428 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.51
ALDH1A1 P00352 2/20 0.51
MAPT P10636 3/20 0.49
NPC1 O15118 2/20 0.49
KDM4E B2RXH2 2/20 0.49
GFER P55789 1/20 0.49
EGFR P00533 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
RAB9A P51151 2/20 0.46
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44
POLB P06746 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5667044 0.98 RAPGEF4 (0.63) RAPGEF4GAAMEN1KMT2AL3MBTL1
SCHEMBL30146931 0.98 RAPGEF4 (0.63) RAPGEF4GAAMEN1KMT2AL3MBTL1
SCHEMBL29445703 0.96 RAPGEF4 (0.65) RAPGEF4GAAMEN1KMT2AL3MBTL1
SCHEMBL1921159 0.96 RAPGEF4 (0.65) RAPGEF4GAAMEN1KMT2AL3MBTL1
SCHEMBL15478852 0.92 RAPGEF4 (0.57) RAPGEF4GAAMEN1KMT2AL3MBTL1
SCHEMBL1921480 0.89 RAPGEF4 (0.59) RAPGEF4GAAMEN1KMT2AL3MBTL1
SCHEMBL15478854 0.87 RAPGEF4 (0.52) RAPGEF4GAAMEN1KMT2AL3MBTL1
SCHEMBL21037121 0.86 RAPGEF4 (0.55) RAPGEF4GAAMEN1KMT2ASMN1; SMN2
SCHEMBL14850476 0.86 RAPGEF4 (0.61) RAPGEF4GAAMEN1KMT2AL3MBTL1
SCHEMBL11563580 0.86 RAPGEF4 (0.55) RAPGEF4GAAMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3158030-B1 USE OF ADDITIVES FOR IMPROVING OXIDATION STABILITY OF PARAFFINIC DIESEL FUEL COMPOSITIONS SHELL INT RESEARCH (NL) 2020-11-25 EP disclosed
WO-2017034023-A1 COMPLEX AND OPTICAL ELEMENT 国立大学法人京都大学 2017-03-02 WO disclosed
US-9382490-B2 Compositions SHELL OIL COMPANY (US) 2016-07-05 US disclosed
US-20150368576-A1 FISCHER TROPSCH DERIVED DIESEL FUEL FORMULATION SHELL OIL COMPANY 2015-12-24 US disclosed
CN-104903430-A Composition comprising a metal oxide and a metal oxide SHELL INT RESEARCH 2015-09-09 CN disclosed
US-20140187454-A1 COMPOSITIONS SHELL OIL COMPANY (US) 2014-07-03 US disclosed
US-20080256846-A1 diesel fuels consisting of a straight-run kerosene, a straight-run light oil, a cracked light oil, a cracked kerosene and hydrodesulphurised products; reducing the amount of particulates in exhaust gas; oxidation stability at high temperature SHELL OIL COMPANY 2008-10-23 US disclosed
US-6274666-B1 COPOLYMER OF VINYL AROMATIC HYDROCARBON AND CONJUGATED DIENE BRIDGESTONE/FIRESTONE, INC. 2001-08-14 US disclosed
EP-0659787-B1 Block copolymers and high shear strength pressure sensitive adhesive compositions comprising them SHELL INT RESEARCH (NL) 2000-09-20 EP disclosed
EP-0696603-B1 Improved adhesive and polymer for adhesives BRIDGESTONE FIRESTONE INC (US) 1999-10-13 EP disclosed
EP-0696603-A1 Improved adhesive and polymer for adhesives BRIDGESTONE/FIRESTONE, INC. (US) 1996-02-14 EP disclosed
EP-0659787-A1 Block copolymers and high shear strength pressure sensitive adhesive compositions comprising them SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1995-06-28 EP disclosed
EP-0243956-B1 ADHESIVE COMPOSITIONS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-12-11 EP disclosed
US-4792584-A BLOCK COPOLYMER OF BUTADIENE AND VINYL AROMATIC HYDROCARBON, TACKIFIER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-12-20 US disclosed
EP-0243956-A2 Adhesive compositions Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-11-04 EP disclosed