Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 15/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methionine SCHEMBL4636642 | 0.81 | KIF11 (0.45) | SMN1; SMN2HIF1AKIF11ALPIPKM | |
| Phenylalanine SCHEMBL464777 | 0.81 | SLC7A5 (0.69) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine SCHEMBL28231547 | 0.81 | SLC7A5 (0.69) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Dl-Phenylalanine SCHEMBL28076342 | 0.81 | SLC7A5 (0.69) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Dl-Phenylalanine SCHEMBL464776 | 0.81 | SLC7A5 (0.69) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Dl-Phenylalanine SCHEMBL29503517 | 0.81 | SLC7A5 (0.69) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL3956933 | 0.81 | SMN1; SMN2 (0.78) | SMN1; SMN2HIF1AALPIPKMPTGS1 | |
| SCHEMBL3956936 | 0.81 | SMN1; SMN2 (0.78) | SMN1; SMN2HIF1AALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL7358357 | 0.79 | SMN1; SMN2 (0.75) | SMN1; SMN2HIF1AALPIPKMPTGS1 | |
| Racemethionine SCHEMBL526136 | 0.78 | ALPI (0.50) | KIF11ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934343-A2 | SELECTIVE POSTTRANSLATIONAL MODIFICATION OF PHAGE-DISPLAYED POLYPEPTIDES | The Scripps Research Institute (US) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007047301-A2 | SELECTIVE POSTTRANSLATIONAL MODIFICATION OF PHAGE-DISPLAYED POLYPEPTIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-04-26 | — | — | WO | disclosed |