Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031511 | 0.90 | HDAC3 (0.51) | HDAC3MAPK1HDAC1HDAC2NPC1 | |
| SCHEMBL9564884 | 0.85 | HDAC1 (0.47) | HDAC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL5026848 | 0.78 | KMT2A (0.47) | HDAC3MAPK1HDAC1HDAC2NPC1 | |
| SCHEMBL5025278 | 0.78 | KMT2A (0.47) | HDAC3MAPK1HDAC1HDAC2NPC1 | |
| SCHEMBL653766 | 0.76 | KMT2A (0.51) | HDAC3MAPK1HDAC1HDAC2NPC1 | |
| SCHEMBL783675 | 0.73 | ADORA3 (0.57) | NPC1RAB9ABCAT2KMT2AMEN1 | |
| SCHEMBL655757 | 0.72 | MITF (0.53) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL29920018 | 0.70 | EGFR (0.58) | NPC1RAB9AKMT2AMEN1HCAR3 | |
| SCHEMBL28936534 | 0.70 | EGFR (0.58) | NPC1RAB9AKMT2AMEN1HCAR3 | |
| SCHEMBL6499835 | 0.69 | EGFR (0.65) | NPC1RAB9AKMT2AMEN1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101438288-A | Regulation of phosphoryl transferase activity of glutamine synthetase | CSIR CORP (ZA) | 2009-05-20 | — | — | CN | disclosed |
| EP-2008210-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |