SCHEMBL5029679

SCHEMBL5029679

CCCC(=O)Oc1ccc2ccccc2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 2/20 0.63
PDGFRA P16234 2/20 0.63
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
ALDH1A1 P00352 2/20 0.58
CYP1A2 P05177 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
MAPT P10636 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
PPARG P37231 2/20 0.53
PPARA Q07869 2/20 0.53
BCL9 O00512 1/20 0.51
CTNNB1 P35222 1/20 0.51
KDM4E B2RXH2 2/20 0.50
GLA P06280 1/20 0.50
GAA P10253 1/20 0.50
CETP P11597 1/20 0.49
RAB9A P51151 1/20 0.49
PTPN7 P35236 1/20 0.49
CA2 P00918 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29914018 1.00 PDGFRB (0.63) PDGFRBPDGFRAKMT2AMEN1ALDH1A1
SCHEMBL9807295 0.90 MEN1 (0.56) PDGFRBPDGFRAKMT2AMEN1ALDH1A1
SCHEMBL5036303 0.89 CETP (0.56) PDGFRBPDGFRAKMT2AMEN1ALDH1A1
SCHEMBL15882797 0.89 PDGFRB (0.55) PDGFRBPDGFRAKMT2AMEN1ALDH1A1
SCHEMBL1826963 0.87 CETP (0.58) PDGFRBPDGFRAKMT2AMEN1ALDH1A1
SCHEMBL22166729 0.87 CETP (0.58) PDGFRBPDGFRAKMT2AMEN1ALDH1A1
SCHEMBL5357930 0.87 CETP (0.58) PDGFRBPDGFRAKMT2AMEN1ALDH1A1
SCHEMBL17702569 0.87 CETP (0.58) PDGFRBPDGFRAKMT2AMEN1ALDH1A1
SCHEMBL1825948 0.87 CETP (0.58) PDGFRBPDGFRAKMT2AMEN1ALDH1A1
SCHEMBL11324211 0.87 CETP (0.58) PDGFRBPDGFRAKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115247192-A Enzymatic preparation technology of acyl/aroyl coenzyme A 中国医学科学院药物研究所 2022-10-28 CN claimed
US-20260137736-A1 PROBIOTIC LACTOBACILLUS STRAIN COMPOSITIONS AND APPLICATIONS THEREFOR INCLUDING FOR LEAKY GUT AND INFLAMMATION BIOMEDIT LLC (US) 2026-05-21 US disclosed
US-12564613-B2 Strains having effects of preventing or treating cancers GENOME AND COMPANY (KR) 2026-03-03 US disclosed
EP-3897156-B1 MICROBACTERIUM ESTERAROMATICUM STRAIN, COMPOSITION COMPRISING THE SAME, AND USES THEREOF FUTURECO BIOSCIENCE S A (ES) 2025-07-09 EP disclosed
US-12214004-B2 Strains having effects of preventing or treating cancers GENOME AND COMPANY (KR) 2025-02-04 US disclosed
US-20230115696-A1 BACTERIAL GENES AND ISOLATES FOR CONFERRING INSECT RESISTANCE EVOGENE LTD. (IL) 2023-04-13 US disclosed
WO-2022228297-A1 ENZYMATIC PREPARATION TECHNIQUE FOR ACYL/AROYL COENZYME A 中国医学科学院药物研究所 2022-11-03 WO disclosed
CN-115247192-A Enzymatic preparation technology of acyl/aroyl coenzyme A 中国医学科学院药物研究所 2022-10-28 CN disclosed
US-11466247-B2 Bacterial genes and isolates for conferring insect resistance EVOGENE LTD. (IL) 2022-10-11 US disclosed
US-20220132862-A1 PSEUDOMONAS SP. STRAIN, COMPOSITION COMPRISING THE SAME, AND USES THEREOF FUTURECO BIOSCIENCE, S.A. (ES) 2022-05-05 US disclosed
WO-1997041214-A1 BIOCATALYSTS WITH AMINE ACYLASE ACTIVITY NOVARTIS AG (CH) 1997-11-06 WO disclosed
EP-0711283-A1 TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS PFIZER INC. (US) 1996-05-15 EP disclosed
EP-0457735-B1 Biocatalytic process for the production of L-(-)-carnitine from crotonobetaine and strains of Proteeae for use in said process SIGMA TAU IND FARMACEUTI (IT) 1995-07-26 EP disclosed
WO-1995003281-A1 TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS PFIZER INC. (US) 1995-02-02 WO disclosed
US-5300430-A Hydration SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1994-04-05 US disclosed
EP-0264168-B1 PROCESS FOR PRODUCING 6-HYDROXY-2-NAPHTHONES CELANESE CORPORATION (US) 1992-05-06 EP disclosed
EP-0457735-A1 Biocatalytic process for the production of L-(-)-carnitine from crotonobetaine and strains of Proteeae for use in said process Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1991-11-21 EP disclosed
EP-0264168-A2 Process for producing 6-hydroxy-2-naphthones CELANESE CORPORATION (US) 1988-04-20 EP disclosed
US-4675449-A FROM 2-NAPHTHYL CARBOXYLATE ESTER CELANESE CORPORATION (US) 1987-06-23 US disclosed
US-4277490-A Insecticidal 1-(2-naphthyl)-cyclobutane carboxylate COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1981-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137736-A1 PROBIOTIC LACTOBACILLUS STRAIN COMPOSITIONS AND APPLICATIONS THEREFOR INCLUDING FOR LEAKY GUT AND INFLAMMATION FABP2, SLC10A2, ALPI PDGFRB 2940/4885PDGFRA 3526/4885KMT2A 3259/4885
US-12214004-B2 Strains having effects of preventing or treating cancers LGALS3, B3GAT3, MKI67 PDGFRB 2908/4885PDGFRA 3168/4885KMT2A 4520/4885
US-12564613-B2 Strains having effects of preventing or treating cancers PDCD1, TOP1, CD274 PDGFRB 3817/4885PDGFRA 4579/4885KMT2A 3502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.