SCHEMBL5029928

SCHEMBL5029928

CC(C)(C)O[Si](Cl)(Oc1ccccc1)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.36
LTA4H P09960 2/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.32
RIPK1 Q13546 1/20 0.32
PAX8 Q06710 1/20 0.31
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1042227 0.79 LTA4H (0.45) CA4LTA4HTSHRPAX8ALDH1A1
SCHEMBL5027521 0.78 CA4 (0.39) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL5032224 0.78 CA4 (0.39) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL3887765 0.77 CA4 (0.37) CA4LTA4HTSHRMAPK1RIPK1
SCHEMBL5027493 0.76 CA4 (0.46) CA4LTA4HTSHRPAX8ALDH1A1
SCHEMBL5032246 0.76 CA4 (0.46) CA4LTA4HTSHRPAX8ALDH1A1
SCHEMBL5030107 0.75 CA4 (0.36) CA4LTA4HTSHRPAX8ALDH1A1
SCHEMBL29059249 0.73 CA4 (0.31) CA4TSHRALDH1A1
SCHEMBL5027548 0.71 LTA4H (0.41) CA4LTA4HTSHRALDH1A1L3MBTL1
SCHEMBL5029761 0.71 LTA4H (0.41) CA4LTA4HTSHRALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 EP disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 US disclosed