Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027521 | 0.95 | CA4 (0.39) | CA4LTA4HTSHRMAPK1RIPK1 | |
| SCHEMBL25253222 | 0.85 | LTA4H (0.36) | CA4LTA4HTSHRMAPK1RIPK1 | |
| SCHEMBL3887765 | 0.80 | CA4 (0.37) | CA4LTA4HTSHRMAPK1RIPK1 | |
| SCHEMBL5029928 | 0.78 | CA4 (0.36) | CA4LTA4HTSHRMAPK1RIPK1 | |
| SCHEMBL301726 | 0.77 | LTA4H (0.50) | CA4LTA4HTSHRALDH1A1ALOX15 | |
| SCHEMBL20513976 | 0.75 | CA4 (0.33) | CA4LTA4HTSHRMAPK1RIPK1 | |
| SCHEMBL15653550 | 0.75 | LTA4H (0.47) | CA4LTA4HTSHRALDH1A1L3MBTL1 | |
| SCHEMBL10323853 | 0.74 | HTT (0.47) | CA4LTA4HTSHRALDH1A1ATM | |
| SCHEMBL10323805 | 0.74 | HTT (0.47) | CA4LTA4HTSHRALDH1A1ATM | |
| SCHEMBL20513150 | 0.74 | ATM (0.34) | CA4LTA4HTSHRATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |