⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5999057 | 0.98 | — | — | |
| SCHEMBL1276611 | 0.93 | — | — | |
| SCHEMBL10896198 | 0.91 | CCR2 (0.44) | — | |
| SCHEMBL27687021 | 0.91 | CCR2 (0.41) | — | |
| SCHEMBL10914489 | 0.91 | CCR2 (0.44) | — | |
| SCHEMBL860303 | 0.84 | — | — | |
| SCHEMBL25811036 | 0.72 | — | — | |
| SCHEMBL20008739 | 0.72 | — | — | |
| SCHEMBL23551725 | 0.72 | — | — | |
| SCHEMBL1632998 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456197-B1 | PIPERIDINE-2,6-DIONES THAT ARE HETEROCYCLICALLY SUBSTITUTED IN POSITION 3 | GRUENENTHAL GMBH (DE) | 2007-02-28 | — | — | EP | claimed |
| US-7183274-B2 | Piperidine-2,6-diones heterocyclically substituted in the 3-position | GRUENENTHAL GMBH (DE) | 2007-02-27 | — | — | US | claimed |
| US-20050020581-A1 | Piperidine-2,6-diones heterocyclically substituted in the 3-position | GRUENENTHAL GMBH (DE) | 2005-01-27 | — | — | US | claimed |
| EP-4323369-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-02-21 | — | — | EP | disclosed |
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C 4 Therapeutics, Inc. (US) | 2024-01-18 | — | — | US | disclosed |
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C 4 Therapeutics, Inc. (US) | 2024-01-18 | — | — | US | disclosed |
| CN-117120450-A | Thienopyrrole compounds | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20230372496-A1 | TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS | C4 THERAPEUTICS, INC. (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230372496-A1 | TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS | C4 THERAPEUTICS, INC. (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230372496-A1 | TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS | C4 THERAPEUTICS, INC. (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230365594-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2023-11-16 | — | — | US | disclosed |
| US-4742174-A | MICROBTOCIDES | TANABE SEIYAKU CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| US-4727071-A | MICROBIOCIDES | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-23 | — | — | US | disclosed |
| EP-0245619-A1 | Novel thiazolylacetic acid derivatives and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1987-11-19 | — | — | EP | disclosed |
| US-4598154-A | Thiazole intermediates for cephalosporin compounds | TANABE SEIYAKU CO., LTD. (JP) | 1986-07-01 | — | — | US | disclosed |
| US-4598075-A | ANTIMICROBIAL | TANABE SEIYAKU CO., LTD. (JP) | 1986-07-01 | — | — | US | disclosed |
| EP-0147181-A2 | Thiazolylacetic acid derivatives and their preparation | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-03 | — | — | EP | disclosed |
| EP-0101265-A2 | Novel cephalosporin compounds and preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1984-02-22 | — | — | EP | disclosed |
| US-4067985-A | IMMUNOSUPPRESSIVE, SEDATIVE, ANTITUMOR | CHEMIE GRUNENTHAL GMBH (DT) | 1978-01-10 | — | — | US | disclosed |
| US-3951985-A | SUBSTITUTED ORTHO-SULFOBENZOIC ACID IMIDO PYRROLIDONE, PIPERIDONE OR CAPROLACTAM | CHEMIE GRUNENTHAL GMBH (DT) | 1976-04-20 | — | — | US | disclosed |