⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029979 | 0.84 | — | — | |
| SCHEMBL1276611 | 0.82 | — | — | |
| Bromide SCHEMBL5999057 | 0.82 | — | — | |
| SCHEMBL10896198 | 0.80 | CCR2 (0.44) | — | |
| SCHEMBL10914489 | 0.80 | CCR2 (0.44) | — | |
| SCHEMBL27687021 | 0.80 | CCR2 (0.41) | — | |
| SCHEMBL31106431 | 0.77 | CRBN (0.33) | — | |
| SCHEMBL2080770 | 0.74 | — | — | |
| SCHEMBL31045631 | 0.73 | PSEN1 (0.31) | — | |
| SCHEMBL1457363 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957481-B1 | PYRROLIDIN(THI)ONES HETEROCYCLICALLY SUBSTITUTED IN 3-POSITION | GRUENENTHAL GMBH (DE) | 2011-03-02 | — | — | EP | claimed |
| US-20080293749-A1 | Pyrrolidine(thi)ones Substituted by Heterocyclic Substituents in The 3-Position | GRUENENTHAL GMBH (DE) | 2008-11-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| EP-0184861-B1 | DERIVATIVES OF THE 3-MERCAPTO-2-OXO-1-PYRROLIDINACETIC ACID, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PROTER S.p.A. (IT) | 1990-06-06 | — | — | EP | claimed |
| EP-0184861-A1 | Derivatives of the 3-mercapto-2-oxo-1-pyrrolidinacetic acid, process for their preparation and pharmaceutical compositions containing them | PROTER S.p.A. (IT) | 1986-06-18 | — | — | EP | claimed |
| JP-62294681-A | — | — | None | — | — | JP | disclosed |
| EP-4630115-A1 | THERAPEUTIC COMPOUNDS | Sanofi (FR) | 2025-10-15 | — | — | EP | disclosed |
| CN-120129535-A | Tissue factor antibody-drug conjugates and uses thereof | 埃克塞里艾克西斯公司 | 2025-06-10 | — | — | CN | disclosed |
| WO-2025106863-A1 | LACTAM DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| US-12281116-B2 | HTT modulators for treating Huntington's disease | CHDI FOUNDATION, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| US-20250057852-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION | 2025-02-20 | — | — | US | disclosed |
| US-20250059157-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2025-02-20 | — | — | US | disclosed |
| US-4598154-A | Thiazole intermediates for cephalosporin compounds | TANABE SEIYAKU CO., LTD. (JP) | 1986-07-01 | — | — | US | disclosed |
| US-4547494-A | BACTERICIDES | TANABE SEIYAKU CO., LTD. (JP) | 1985-10-15 | — | — | US | disclosed |
| EP-0147181-A2 | Thiazolylacetic acid derivatives and their preparation | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-03 | — | — | EP | disclosed |
| EP-0117109-A2 | Novel cephalosporin compound and a process for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1984-08-29 | — | — | EP | disclosed |
| EP-0101265-A2 | Novel cephalosporin compounds and preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1984-02-22 | — | — | EP | disclosed |
| EP-0085840-A1 | New 6-substituted-s-triazolo(3,4-a)phthalazine derivatives | GRUPPO LEPETIT S.P.A. (IT) | 1983-08-17 | — | — | EP | disclosed |
| US-4067985-A | IMMUNOSUPPRESSIVE, SEDATIVE, ANTITUMOR | CHEMIE GRUNENTHAL GMBH (DT) | 1978-01-10 | — | — | US | disclosed |
| US-3951985-A | SUBSTITUTED ORTHO-SULFOBENZOIC ACID IMIDO PYRROLIDONE, PIPERIDONE OR CAPROLACTAM | CHEMIE GRUNENTHAL GMBH (DT) | 1976-04-20 | — | — | US | disclosed |