SCHEMBL5030128

SCHEMBL5030128

O=C(Cl)Oc1ccc(C(=O)O)cc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.49
KDM4E B2RXH2 3/20 0.49
RAB9A P51151 2/20 0.49
GAA P10253 2/20 0.49
ALDH1A1 P00352 1/20 0.49
CFD P00746 2/20 0.47
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA4 P22748 2/20 0.47
CA6 P23280 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
TPMT P51580 1/20 0.47
HTT P42858 2/20 0.43
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
PTPN11 Q06124 1/20 0.42
FOLH1 Q04609 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11701778 0.91 CFD (0.46) TSHRKDM4ERAB9AGAAALDH1A1
SCHEMBL11702442 0.85 ESR1 (0.50) TSHRKDM4ERAB9AGAAALDH1A1
SCHEMBL11701410 0.85 TSHR (0.67) TSHRKDM4ERAB9AGAAALDH1A1
SCHEMBL11705005 0.81 TTR (0.57) TSHRKDM4ERAB9AGAAALDH1A1
SCHEMBL11275036 0.81 ESR1 (0.50) TSHRKDM4ERAB9AGAAALDH1A1
SCHEMBL11704990 0.81 CFD (0.47) TSHRKDM4EGAAALDH1A1CFD
SCHEMBL2588487 0.80 CA12 (0.53) TSHRKDM4ERAB9AGAAALDH1A1
SCHEMBL9179660 0.79 MAPT (0.35) TSHRKDM4ERAB9AGAAALDH1A1
SCHEMBL4865593 0.77 TSHR (0.53) TSHRKDM4ERAB9AGAAALDH1A1
SCHEMBL11278084 0.77 KDM4E (0.54) TSHRKDM4ERAB9AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7348113-B2 Electrophotographic photoconductor comprising a polycarbonate resin having a dihydroxy diphenyl ether unit RICOH COMPANY, LTD. (JP) 2008-03-25 US disclosed
US-7071285-B2 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2006-07-04 US disclosed
US-6919419-B2 AROMATIC BLOCK POLYCARBONATE RESIN, DIPHENOL COMPOUND FOR PREPARATION OF THE POLYCARBONATE RESIN, ELECTRO-PHOTOGRAPHIC PHOTOCONDUCTOR, ELECTRO-PHOTOGRAPHIC IMAGE FORMING APPARATUS AND PROCESS, AND PROCESS CARTRIDGE RICOH COMPANY LTD. (JP) 2005-07-19 US disclosed
US-20050106483-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, dihydroxy diphenyl ether compound, and process of manufacturing dihydroxy diphenyl ether compound RICOH COMPANY, LTD. (JP) 2005-05-19 US disclosed
US-20050003287-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2005-01-06 US disclosed
US-6790571-B2 FORMED FROM N-(4-(2,2-BIS(4-HYDROXYPHENYL)VINYL)PHENYL)-N,N BIS(4-TOLYL)AMINE; IMPROVED DURABILITY; FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICE RICOH COMPANY, LTD. (JP) 2004-09-14 US disclosed
US-20040002574-A1 Aromatic block polycarbonate resin, diphenol compound for preparation of the polycarbonate resin, electro-photographic photoconductor, electro-photographic image forming apparatus and process, and process cartridge RICOH COMPANY, LTD. (JP) 2004-01-01 US disclosed
US-6664361-B2 Aromatic polycarbonates; electrography RICOH COMPANY, LTD. (JP) 2003-12-16 US disclosed
US-6576386-B1 AROMATIC BLOCK POLYCARBONATE RESIN, DIPHENOL COMPOUND FOR PREPARATION OF THE POLYCARBONATE RESIN, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS AND PROCESS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2003-06-10 US disclosed
US-6486293-B1 Electrophotographic photoconductor and method of producing aromatic polycarbonate resin for use in the photoconductor RICOH COMPANY, LTD. (JP) 2002-11-26 US disclosed
US-6066428-A PHOTOCONDUCTOR COMPRISING ELECTROCONDUCTIVE SUPPORT WITH PHOTOCONDUCTIVE LAYER COMPRISING AROMATIC POLYCARBONATE RESIN HAVING CHARGE TRANSPORT PROPERTIES RICOH COMPANY, LTD. (JP) 2000-05-23 US disclosed
US-6045959-A CHARGE TRANSPORTING POLYMER RICOH COMPANY, LTD. (JP) 2000-04-04 US disclosed
US-6027846-A HIGH PHOTOSENSITIVITY, HIGH DURABILITY RICOH COMPANY, LTD. (JP) 2000-02-22 US disclosed
US-6018014-A PRESCRIBED DIOL MONOMER HAS STRUCTURE HYDROXY-(ARYLENE)-(2-(AMINOARYL OR HETEROCYCLE)VINYL)-(ARYLENE)-HYDROXYL;USEFUL FOR A CHARGE-TRANSPORT POLYMER MATERIAL FOR AN ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEDIUM RICOH COMPANY, LTD. (JP) 2000-01-25 US disclosed
US-5976746-A ELECTROCONDUCTIVE SUPPORT; PHOTOCONDUCTIVE LAYER RICOH COMPANY, LTD. (JP) 1999-11-02 US disclosed
US-5840454-A Aromatic polycarbonate and electrophotographic photosensitive medium using same RICOH COMPANY, LTD. (JP) 1998-11-24 US disclosed
EP-0600447-B1 Aromatic polycarbonate and production method thereof MITSUI CHEMICALS INC (JP) 1998-10-07 EP disclosed
US-5426170-A Interfacial polymerization of aromatic dihydroxy compound, carbonate precursor, alkali metal or alkaline metal base, water and solvent, endcapping MITSUI TOATSU CHEMICALS, INC. (JP) 1995-06-20 US disclosed
EP-0600447-A2 Aromatic polycarbonate and production method thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-06-08 EP disclosed
US-4059565-A Process for producing a branched polycarbonate or poly(ester-carbonate) MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-11-22 US disclosed