SCHEMBL5030171

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5030003	0.89	MAPK1 (0.41)	DCAF1MAPK1ROCK1ROCK2
	SCHEMBL6426273	0.89	MAPK1 (0.41)	DCAF1MAPK1ROCK1ROCK2
	SCHEMBL5029960	0.87	MAPK1 (0.43)	DCAF1MAPK1
	SCHEMBL6428642	0.84	DCAF1 (0.40)	DCAF1MAPK1PAK4
	SCHEMBL5029993	0.83	MEN1 (0.36)	MAPK1PAK4ALDH1A1LMNAHPGD
	SCHEMBL5034325	0.81	MAPK1 (0.43)	MAPK1TACR3ROCK1ROCK2
	SCHEMBL13927708	0.81	MAPK1 (0.43)	MAPK1TACR3ROCK1ROCK2
	SCHEMBL5030009	0.80	MAPK1 (0.43)	DCAF1MAPK1ROCK1ROCK2
	SCHEMBL6428698	0.80	GPR88 (0.44)	DCAF1MAPK1PAK4ROCK1ROCK2
	SCHEMBL5032386	0.80	LMNA (0.35)	MAPK1ALDH1A1LMNAHPGDCDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.