Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 4/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18717064 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL28830141 | 0.81 | TRIM24 (0.56) | ALDH1A1TSHRLMNATDP1TRIM24 | |
| SCHEMBL28280107 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL13589808 | 0.81 | TRIM24 (0.56) | ALDH1A1TSHRLMNATDP1TRIM24 | |
| SCHEMBL11744871 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL5203307 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRERN1CYP1A2CYP2C9 | |
| SCHEMBL21294253 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL28178629 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRERN1CYP1A2CYP2C9 | |
| SCHEMBL11744877 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL28220952 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214708-A1 | Asymmetrically substituted phosphinic acids | CLARIANT INTERNATIONAL LTD. | 2008-09-04 | — | — | US | disclosed |