Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.56 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13589808 | 1.00 | TRIM24 (0.56) | TRIM24TRIM33ALDH1A1TSHRMAPT | |
| SCHEMBL5030176 | 0.81 | ALDH1A1 (0.57) | TRIM24TRIM33ALDH1A1TSHRMAPT | |
| SCHEMBL28280107 | 0.79 | ALDH1A1 (0.56) | TRIM24TRIM33ALDH1A1TSHRMAPT | |
| SCHEMBL13589834 | 0.78 | TRIM24 (0.60) | TRIM24TRIM33ALDH1A1MAPTLMNA | |
| SCHEMBL276965 | 0.78 | TRIM24 (0.52) | TRIM24TRIM33ALDH1A1MAPTLMNA | |
| SCHEMBL31000832 | 0.78 | TRIM24 (0.52) | TRIM24TRIM33ALDH1A1MAPTLMNA | |
| SCHEMBL11744877 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTLMNACA2 | |
| SCHEMBL5203307 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTERN1NFE2L2 | |
| SCHEMBL21294253 | 0.78 | ALDH1A1 (0.53) | TRIM24TRIM33ALDH1A1TSHRMAPT | |
| SCHEMBL11744871 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTLMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105611923-B | Sodium channel modulators for the treatment of pain and diabetes | 卓莫赛尔公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-105611923-A | Sodium channel modulators for the treatment of pain and diabetes | CHROMOCELL CORP | 2016-05-25 | — | — | CN | disclosed |