Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.85 |
| ▸ | CRHBP | P24387 | 2/20 | 0.85 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.85 |
| ▸ | HTT | P42858 | 2/20 | 0.85 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.70 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.70 |
| ▸ | ITGAL | P20701 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896371 | 1.00 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL1262733 | 1.00 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL35510 | 1.00 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL35680 | 1.00 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL35766 | 1.00 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL35802 | 1.00 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL288378 | 1.00 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL896445 | 1.00 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL15301625 | 1.00 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL2167630 | 0.98 | LMNA (0.81) | LMNASMN1; SMN2CRHBPCRHR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4970131-A | CROWN ETHER OR POLYETHER | RICOH COMPANY, LTD. (JP) | 1990-11-13 | — | — | US | claimed |
| US-4863822-A | Electrophotographic photoconductor comprising charge generating and transport layers containing adjuvants | RICOH COMPANY LTD. (JP) | 1989-09-05 | — | — | US | claimed |
| US-7348115-B2 | Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method | RICOH COMPANY, LTD. (JP) | 2008-03-25 | — | — | US | disclosed |
| US-7267914-B2 | Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method | RICOH COMPANY, LTD. (JP) | 2007-09-11 | — | — | US | disclosed |
| US-20050170271-A1 | Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method | YAMANAMI HIROFUMI (JP) | 2005-08-04 | — | — | US | disclosed |
| US-20030232265-A1 | Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method | RICOH COMPANY, LTD. (JP) | 2003-12-18 | — | — | US | disclosed |
| EP-1324139-A2 | Electrophotographic photoconductor, process cartridge, image forming apparatus and image forming method | Ricoh Company, Ltd. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-4863822-A | Electrophotographic photoconductor comprising charge generating and transport layers containing adjuvants | RICOH COMPANY LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0071178-B1 | ACYLOXYSTEROIDS AND PROCESS FOR PRODUCING SAME | MITSUBISHI KASEI CORPORATION (JP) | 1985-10-16 | — | — | EP | disclosed |