Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.81 |
| ▸ | CRHBP | P24387 | 2/20 | 0.81 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.81 |
| ▸ | HTT | P42858 | 2/20 | 0.81 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.67 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.67 |
| ▸ | ITGAL | P20701 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030177 | 0.98 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL35510 | 0.98 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL288378 | 0.98 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL35680 | 0.98 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL35766 | 0.98 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL15301625 | 0.98 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL35802 | 0.98 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL896445 | 0.98 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL1262733 | 0.98 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL896371 | 0.98 | LMNA (0.85) | LMNASMN1; SMN2CRHBPCRHR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110179697-A1 | Method for Production of Metallocenes Preventing Nitrogen Oxides Emission in Combustion of Fuels in Motors | Asiacom Group Investments, Inc. | 2011-07-28 | — | — | US | disclosed |
| WO-2007077485-A2 | METHOD FOR PRODUCING METALLOCENES | PROPERTY DEVELOPMENT CORPORATION INTERNATIONAL LTD, INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| US-7157592-B1 | Ferrocene is produced from a mixture of ferrous chloride, cyclopentadiene anion, diethylamine, and dibenzo-18-crown-6-potassium complex, with further petroleum ether extraction of the prepared product; efficiency | PROPERTY DEVELOPMENT CORPORATION INTERNATIONAL LTD., INC. (AZ) | 2007-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110179697-A1 | Method for Production of Metallocenes Preventing Nitrogen Oxides Emission in Combustion of Fuels in Motors | SOD1, CYC1, NDUFS8 | LMNA 2712/4885SMN1; SMN2 268/4885CRHBP 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.