SCHEMBL7902133

SCHEMBL7902133

Cc1cccc2sc(C#N)nc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 2/20 0.65
ALDH1A1 P00352 4/20 0.56
MAPT P10636 7/20 0.48
PKM P14618 1/20 0.46
GAA P10253 2/20 0.44
MEN1 O00255 8/20 0.42
KMT2A Q03164 8/20 0.42
KDM4E B2RXH2 4/20 0.42
ALOX15 P16050 3/20 0.42
POLB P06746 3/20 0.42
LMNA P02545 3/20 0.42
HPGD P15428 3/20 0.42
USP2 O75604 2/20 0.42
HSD17B10 Q99714 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
MCL1 Q07820 1/20 0.42
ESR2 Q92731 1/20 0.42
MAPK1 P28482 1/20 0.42
XBP1 P17861 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28849254 0.80 PSMB8 (0.67) PSMB8ALDH1A1MAPTPKMGAA
SCHEMBL30874518 0.80 PSMB8 (0.67) PSMB8ALDH1A1MAPTPKMGAA
SCHEMBL5030198 0.79 PSMB8 (0.65) PSMB8ALDH1A1MAPTPKMGAA
SCHEMBL441613 0.79 PSMB8 (0.65) PSMB8ALDH1A1MAPTPKMGAA
SCHEMBL10574548 0.79 PSMB8 (0.65) PSMB8ALDH1A1MAPTPKMGAA
SCHEMBL23452413 0.79 PSMB8 (1.00) PSMB8ALDH1A1MAPTPKMGAA
SCHEMBL11709639 0.78 PSMB8 (0.59) PSMB8ALDH1A1MAPTPKMGAA
SCHEMBL22127190 0.78 ALDH1A1 (0.59) PSMB8ALDH1A1MAPTGAAMEN1
Thiocyanic Acid SCHEMBL27730869 0.76 ALDH1A1 (0.53) PSMB8ALDH1A1MAPTPKMGAA
SCHEMBL29241840 0.75 ALDH1A1 (0.56) PSMB8ALDH1A1MAPTPKMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1116366-C Pyridone-methide azo dyestuffs BAYER AG (DE) 2003-07-30 CN disclosed
US-6201126-B1 Isoindolenineamide dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 2001-03-13 US disclosed