Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | MELK | Q14680 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025534 | 0.76 | TAS2R14 (0.40) | GRIN2BACACB | |
| SCHEMBL5025529 | 0.76 | TAS2R14 (0.40) | GRIN2BACACB | |
| SCHEMBL5030212 | 0.72 | TAS2R14 (0.38) | GRIN2B | |
| SCHEMBL5028491 | 0.69 | GRIN2B (0.35) | GRIN2BACACB | |
| SCHEMBL5762331 | 0.66 | GRIN2B (0.32) | GRIN2BACACB | |
| SCHEMBL5762324 | 0.66 | GRIN2B (0.32) | GRIN2BACACB | |
| SCHEMBL5028487 | 0.66 | GRIN2B (0.35) | GRIN2BACACBCDK12 | |
| SCHEMBL12503235 | 0.65 | ALDH1A1 (0.39) | ACACBHCAR3 | |
| SCHEMBL5026543 | 0.65 | TAS2R14 (0.35) | — | |
| SCHEMBL5026538 | 0.65 | TAS2R14 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442791-B2 | Aminoalkylamide substituted cyclohexyl derivatives | HOFFMANN-LA ROCHE INC. (US) | 2008-10-28 | — | — | US | disclosed |