Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30773476 | 0.86 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL892877 | 0.86 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL5030423 | 0.82 | ALDH1A1 (0.36) | — | |
| SCHEMBL6451965 | 0.78 | EPHX1 (0.38) | TLR7TLR8 | |
| SCHEMBL4794141 | 0.72 | BRD4 (0.30) | TLR7 | |
| SCHEMBL5337899 | 0.70 | EPHX2 (0.44) | TLR7 | |
| SCHEMBL6448983 | 0.68 | TLR8 (0.36) | TLR7TLR8 | |
| SCHEMBL13996160 | 0.68 | EPHX1 (0.40) | TLR7TLR8 | |
| SCHEMBL4791571 | 0.66 | TLR7 (0.38) | TLR7TLR8 | |
| SCHEMBL5336577 | 0.65 | TLR7 (0.36) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312434-A1 | PROCESS FOR IMIDAZO [4,5-C] PYRIDIN-4-AMINES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312434-A1 | PROCESS FOR IMIDAZO [4,5-C] PYRIDIN-4-AMINES | PAICS, HTR4, PNPO | TLR7 974/4885TLR8 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.