⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23375930 | 1.00 | — | — | |
| SCHEMBL14625154 | 1.00 | — | — | |
| SCHEMBL1070569 | 0.87 | ALOX5 (0.30) | — | |
| SCHEMBL7712024 | 0.86 | — | — | |
| SCHEMBL14624669 | 0.86 | — | — | |
| SCHEMBL4010095 | 0.83 | — | — | |
| SCHEMBL9428121 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL11714061 | 0.74 | NCF1 (0.36) | — | |
| SCHEMBL18970297 | 0.69 | — | — | |
| SCHEMBL2771599 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105152846-A | Method for efficiently preparing cylopropyl ethylnen | JIUJIANG ZHONGTIAN PHARMACEUTICAL CO LTD | 2015-12-16 | — | — | CN | claimed |
| CN-103044230-B | Preparation method of 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone | HUNAN CHEMICAL ENGINEERING INST. (CN) | 2014-10-08 | — | — | CN | claimed |
| CN-103044230-A | Preparation method of 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone | HUNAN RES INST CHEMICAL IND | 2013-04-17 | — | — | CN | claimed |
| US-5288932-A | Halogenation a hydroxymethyl cyclopropane with methane sulfonyl halide in the presence of trialkylamine in one pot, without isolation the mesyl halide | HUELS AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | claimed |
| CN-223417234-U | Feeding control structure applicable to chlorocyclopropyl ethanone processing catalyst | 乐平荣凯科技有限公司 | 2025-10-10 | — | — | CN | disclosed |
| CN-109400542-B | Preparation method of cyproconazole | 淮安国瑞化工有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-109535091-B | Method for synthesizing cyproconazole by using 1- (4-chlorphenyl) -2- (1H-1,2, 4-triazole-1-yl) ethanone | 淮安国瑞化工有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-209128342-U | A kind of reaction unit being lower than raw material for product boiling point | 浙江华海天诚药业有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-109400542-A | Novel preparation method of cyproconazole | 淮安国瑞化工有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-106554345-B | A kind of recycling of phosphorus pentachloride chlorinated secondary product and the method utilized | 杭州杜易科技有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-108530283-A | A kind of 1-（4- chlorphenyls）The synthetic method of -2- cyclopropyl -1- acetone | 山东潍坊润丰化工股份有限公司 | 2018-09-14 | — | — | CN | disclosed |
| CN-105820128-B | A kind of preparation method of cyproconazole | 江西华士药业有限公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-1183090-C | Method for preparation of cyclopropyl acrylic derivative | �����ɷ� | 2005-01-05 | — | — | CN | disclosed |
| CN-1129567-C | Process for preparation of cyclopropylacetylene derivatives | KURARAY CO (JP) | 2003-12-03 | — | — | CN | disclosed |
| CN-1070833-C | Process for preparing cyclopropyl acetylene derivatives | KURARAY CO (JP) | 2001-09-12 | — | — | CN | disclosed |
| CN-1281846-A | Method for preparation of cyclopropyl acrylic derivative | KURARAY CO (JP) | 2001-01-31 | — | — | CN | disclosed |
| CN-1281840-A | Process for preparation of cyclopropyl acethlene derivative | KURARAY CO (JP) | 2001-01-31 | — | — | CN | disclosed |
| CN-1232815-A | Process for preparation of cyclopropylacetylene derivatives | KURARAY CO (JP) | 1999-10-27 | — | — | CN | disclosed |
| CN-1191856-A | Process for preparing cyclopropyl acetylene derivatives | KURARAY CO (JP) | 1998-09-02 | — | — | CN | disclosed |
| US-3959300-A | Novel indolobenzazepine derivatives, useful as tranquilizers | ENDO LABORATORIES, INC. (US) | 1976-05-25 | — | — | US | disclosed |