Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031242 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ABLMCYP3A4CYP1A2 | |
| SCHEMBL2844022 | 0.87 | BLM (0.59) | SMN1; SMN2HIF1ABLMCYP3A4CYP1A2 | |
| SCHEMBL5844669 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1ABLMCYP3A4CYP1A2 | |
| SCHEMBL27616082 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1ABLMCYP3A4CYP1A2 | |
| SCHEMBL2844025 | 0.87 | BLM (0.59) | SMN1; SMN2HIF1ABLMCYP3A4CYP1A2 | |
| SCHEMBL4937591 | 0.86 | SMN1; SMN2 (0.66) | SMN1; SMN2HIF1ABLMCYP3A4CYP1A2 | |
| SCHEMBL6464407 | 0.86 | SMN1; SMN2 (0.66) | SMN1; SMN2HIF1ABLMCYP3A4CYP1A2 | |
| SCHEMBL5844647 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ABLMCYP3A4CYP1A2 | |
| SCHEMBL16553913 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ABLMCYP3A4CYP1A2 | |
| SCHEMBL5843911 | 0.85 | CYP3A4 (0.49) | SMN1; SMN2HIF1ABLMCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | claimed |
| CN-1812979-A | Substituted aminocarboxylic acids as inhibitors of protein tyrosine phosphatase-1B | INST PHARM DISCOVERY INC (US) | 2006-08-02 | — | — | CN | disclosed |