⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034602 | 0.81 | — | — | |
| SCHEMBL5031351 | 0.73 | — | — | |
| SCHEMBL13527454 | 0.72 | — | — | |
| SCHEMBL4540777 | 0.70 | POLB (0.33) | — | |
| SCHEMBL13996165 | 0.67 | KMT2A (0.33) | — | |
| SCHEMBL1644184 | 0.52 | POLB (0.35) | — | |
| SCHEMBL11525181 | 0.51 | POLB (0.38) | — | |
| SCHEMBL16166384 | 0.51 | POLB (0.34) | — | |
| SCHEMBL13779889 | 0.49 | NTRK1 (0.34) | — | |
| SCHEMBL6288650 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312434-A1 | PROCESS FOR IMIDAZO [4,5-C] PYRIDIN-4-AMINES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-12-18 | — | — | US | disclosed |
| US-20050032829-A1 | Process for imidazo[4,5-c]pyridin-4-amines | 3M INNOVATIVE PROPERTIES COMPANY | 2005-02-10 | — | — | US | disclosed |