⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031317 | 0.81 | — | — | |
| SCHEMBL5034598 | 0.77 | PKM (0.32) | — | |
| SCHEMBL13527455 | 0.76 | MEN1 (0.30) | — | |
| SCHEMBL5031360 | 0.76 | PKM (0.31) | — | |
| SCHEMBL14419213 | 0.75 | KMT2A (0.31) | — | |
| SCHEMBL4243097 | 0.74 | ALDH1A1 (0.34) | — | |
| SCHEMBL13996162 | 0.74 | — | — | |
| SCHEMBL5030340 | 0.74 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL5030399 | 0.72 | BRD4 (0.38) | — | |
| SCHEMBL5027830 | 0.72 | BRD4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312434-A1 | PROCESS FOR IMIDAZO [4,5-C] PYRIDIN-4-AMINES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-12-18 | — | — | US | disclosed |
| US-20050032829-A1 | Process for imidazo[4,5-c]pyridin-4-amines | 3M INNOVATIVE PROPERTIES COMPANY | 2005-02-10 | — | — | US | disclosed |