Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27762061 | 0.85 | GPR84 (0.44) | GPR84PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL3922879 | 0.78 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL2198958 | 0.78 | PI4KA (0.40) | GPR84PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10875892 | 0.75 | PNP (0.47) | GPR84PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9406871 | 0.73 | PI4KA (0.48) | GPR84PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12495463 | 0.72 | TLR8 (0.47) | ALDH1A1HPGDTLR8TLR7MAPT | |
| SCHEMBL16487356 | 0.72 | PI4KA (0.65) | GPR84PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL27741346 | 0.72 | PI4KA (0.65) | GPR84PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16984496 | 0.71 | DHFR (0.39) | PI4KAPI4K2BPI4K2API4KBTLR8 | |
| SCHEMBL27761904 | 0.71 | PI4KA (0.52) | GPR84PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101438288-A | Regulation of phosphoryl transferase activity of glutamine synthetase | CSIR CORP (ZA) | 2009-05-20 | — | — | CN | disclosed |
| EP-2008210-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |