Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23205897 | 0.84 | — | — | |
| SCHEMBL856427 | 0.80 | ALDH1A1 (0.39) | SELEVCAM1POLBOPRK1RXFP1 | |
| SCHEMBL3641399 | 0.77 | SELE (0.40) | SELEVCAM1POLBOPRK1RXFP1 | |
| SCHEMBL856076 | 0.76 | SELE (0.39) | SELEVCAM1POLBOPRK1RXFP1 | |
| SCHEMBL503147 | 0.76 | — | — | |
| SCHEMBL26757905 | 0.76 | — | — | |
| SCHEMBL1350019 | 0.75 | — | — | |
| SCHEMBL7766739 | 0.74 | SELE (0.38) | SELEVCAM1POLBOPRK1RXFP1 | |
| SCHEMBL372414 | 0.74 | SELE (0.38) | SELEVCAM1POLBOPRK1RXFP1 | |
| SCHEMBL13064098 | 0.74 | SELE (0.35) | SELEVCAM1POLBOPRK1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11292853-A | — | — | None | — | — | JP | disclosed |
| EP-2668179-B1 | NEW 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INT (DE) | 2017-08-16 | — | — | EP | disclosed |
| EP-2668179-B1 | NEW 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INT (DE) | 2017-08-16 | — | — | EP | disclosed |
| EP-2528903-B1 | 5-ALKYNYL-PYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2016-07-20 | — | — | EP | disclosed |
| EP-2528903-B1 | 5-ALKYNYL-PYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2016-07-20 | — | — | EP | disclosed |
| US-20160199383-A1 | 5-ALKYNYL-PYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2016-07-14 | — | — | US | disclosed |
| US-20160199383-A1 | 5-ALKYNYL-PYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2016-07-14 | — | — | US | disclosed |
| US-20160199383-A1 | 5-ALKYNYL-PYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2016-07-14 | — | — | US | disclosed |
| US-9321771-B2 | 5-alkynyl-pyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-26 | — | — | US | disclosed |
| US-9321771-B2 | 5-alkynyl-pyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-26 | — | — | US | disclosed |
| WO-2011092197-A1 | 5-ALKYNYL PYRIMIDINES AND THEIR USE AS KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |
| WO-2011092197-A1 | 5-ALKYNYL PYRIMIDINES AND THEIR USE AS KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |
| EP-1074546-B1 | 5-IODO-4-PHENETHYLAMINOPYRIMIDINE DERIVATIVES, INTERMEDIATES THEREOF, PROCESS FOR PRODUCING THE SAME AND AGRICULTURAL/HORTICULTURAL PESTICIDES | UBE INDUSTRIES (JP) | 2006-09-06 | — | — | EP | disclosed |
| US-6521627-B1 | Insecticidal, acaricidal, nematocidal and fungicidal activities | UBE INDUSTRIES, LTD. (JP) | 2003-02-18 | — | — | US | disclosed |
| EP-1074546-A1 | 5-IODO-4-PHENETHYLAMINOPYRIMIDINE DERIVATIVES, INTERMEDIATES THEREOF, PROCESS FOR PRODUCING THE SAME AND AGRICULTURAL/HORTICULTURAL PESTICIDES | Ube Industries, Ltd. (JP) | 2001-02-07 | — | — | EP | disclosed |
| JP-H11292853-A | 4-CHLORO-5-IODO-6-(ALPHA-SUBSTITUTED ETHYL)PYRIMIDINE AND ITS PRODUCTION | UBE IND LTD | 1999-10-26 | — | — | JP | disclosed |
| US-5852023-A | Cyclohexylamino and cycloalkoxy nitrogen heterocycles, processes for their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| CN-1179773-A | Cyclohexylamino and cyclohexylalkoxy nitrogen heterocycles, methods of preparing them and their use as pest-control agents and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-04-22 | — | — | CN | disclosed |
| US-5468751-A | Aminopyrimidine derivatives as microbicides, insecticides and acaricides | CIBA-GEIGY CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |
| WO-1993022291-A1 | ARTHROPODICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160199383-A1 | 5-ALKYNYL-PYRIMIDINES | MKI67, CCNA1, CCNT1 | SELE 3167/4885VCAM1 2202/4885POLB 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.