Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 9/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011397 | 0.92 | LMNA (0.49) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL28469692 | 0.92 | LMNA (0.54) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL619959 | 0.88 | LMNA (0.58) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL11292903 | 0.86 | LMNA (0.59) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL9513442 | 0.85 | LMNA (0.55) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL1359643 | 0.85 | LMNA (0.55) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL9191548 | 0.84 | LMNA (0.54) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| Malonic Acid SCHEMBL11131957 | 0.82 | LMNA (0.53) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL32668972 | 0.82 | LMNA (0.53) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL8063055 | 0.82 | LMNA (0.53) | LMNACYP2C19HIF1AMAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104853-A1 | PROCESSES FOR THE PREPARATION OF PURE IOVERSOL | WOCKHARDT RESEARCH CENTRE (IN) | 2008-09-04 | — | — | WO | disclosed |