SCHEMBL503194

SCHEMBL503194

N[C@@H](Cn1cncn1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EGLN3 Q9H6Z9 1/20 0.50
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA4 P48058 1/20 0.41
GRIK5 Q16478 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
FDPS P14324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14489820 1.00 EGLN3 (0.50) EGLN3GRIA1GRIA2GRIA4GRIK5
SCHEMBL941137 1.00 EGLN3 (0.50) EGLN3GRIA1GRIA2GRIA4GRIK5
Hydrochloric Acid SCHEMBL25425659 0.98 EGLN3 (0.49) EGLN3GRIA1GRIA2GRIA4GRIK5
SCHEMBL27535957 0.82 EGLN3 (0.55) EGLN3MEN1KMT2AALDH1A1HDAC1
SCHEMBL2302721 0.82 EGLN3 (0.56) EGLN3GRIA1GRIA2GRIA4GRIK5
SCHEMBL23009540 0.82 EGLN3 (0.43) EGLN3MEN1KMT2AALDH1A1HDAC1
SCHEMBL15208002 0.82 EGLN3 (0.56) EGLN3GRIA1GRIA2GRIA4GRIK5
SCHEMBL2300220 0.81 EGLN3 (0.54) EGLN3MEN1KMT2A
SCHEMBL2300214 0.81 EGLN3 (0.54) EGLN3MEN1KMT2A
SCHEMBL16343554 0.80 MEN1 (0.42) EGLN3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY FELDAN BIO INC. (CA) 2024-06-20 US claimed
CN-117750978-A Synthetic peptide shuttle bioconjugates for intracellular cargo delivery 费尔丹生物公司 2024-03-22 CN claimed
EP-4313159-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY Feldan Bio Inc. (CA) 2024-02-07 EP claimed
US-20230399661-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS FELDAN BIO INC. (CA) 2023-12-14 US claimed
US-20230383291-A1 PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION FELDAN BIO INC. (CA) 2023-11-30 US claimed
EP-4232590-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS Feldan Bio Inc. (CA) 2023-08-30 EP claimed
CN-116615205-A Peptide-based transduction of non-anionic polynucleotide analogs for modulation of gene expression 费尔丹生物公司 2023-08-18 CN claimed
CN-116615227-A Minimum length shuttle peptide suitable for transduction of Cas9-RNP and other nucleoprotein loads and variants thereof 费尔丹生物公司 2023-08-18 CN claimed
WO-2022204806-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY FELDAN BIO INC. (CA) 2022-10-06 WO claimed
US-20220204561-A1 PEPTIDE-BASED NON-PROTEINACEOUS CARGO DELIVERY FELDAN BIO INC. (CA) 2022-06-30 US claimed
WO-2022082315-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS FELDAN BIO INC. (CA) 2022-04-28 WO claimed
EP-3970801-A1 RAS INHIBITORY PEPTIDE Ichimaru Pharcos Co., Ltd. (JP) 2022-03-23 EP claimed
CN-114008210-A Peptide-based non-protein cargo delivery 费尔丹生物公司 2022-02-01 CN claimed
CN-113727991-A Ras inhibitory peptide 一丸自然美健有限公司 2021-11-30 CN claimed
WO-2020230780-A1 Ras INHIBITORY PEPTIDE 一丸ファルコス株式会社 2020-11-19 WO claimed
EP-3335720-A1 C-DI-GMP BINDING PEPTIDES Universität Basel (CH) 2018-06-20 EP claimed
EP-3727462-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLERD LTD (GB) 2025-11-05 EP disclosed
US-12459974-B2 Bicyclic peptide ligands specific for Nectin-4 BICYCLETX LIMITED (GB) 2025-11-04 US disclosed
US-6153591-A PROTECTING NERVOUS SYSTEM FOLLOWING FOCAL ISCHEMIA AND GLOBAL ISCHEMIA; ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, PRION DISEASES, PARKINSON'S DISEASE, MULTIPLE SCLEROSIS, AMYOTROPHIC LATERAL SCLEROSIS, ALOPACIA, RHEUMATOID ARTHRITIS CYTOVIA, INC. (US) 2000-11-28 US disclosed
WO-1999047154-A1 DIPEPTIDE CASPASE INHIBITORS AND THE USE THEREOF CYTOVIA, INC. (US) 1999-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12459974-B2 Bicyclic peptide ligands specific for Nectin-4 NECTIN4, VCAM1, SIGLEC7 EGLN3 4139/4885GRIA1 1183/4885GRIA2 1296/4885
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY SCAMP2, SLC7A1, NUMA1 EGLN3 4401/4885GRIA1 2216/4885GRIA2 2569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.