Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25335375 | 0.88 | TRPV1 (0.47) | TRPV1HPGDL3MBTL1GLASMN1; SMN2 | |
| SCHEMBL5034532 | 0.86 | L3MBTL1 (0.50) | HPGDL3MBTL1SMN1; SMN2ALDH1A1PLAAT3 | |
| SCHEMBL4352379 | 0.85 | TRPV1 (0.65) | TRPV1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL2019835 | 0.85 | TRPV1 (0.69) | TRPV1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL893485 | 0.83 | TRPV1 (0.72) | TRPV1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL2024980 | 0.83 | TRPV1 (0.72) | TRPV1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL1936140 | 0.83 | L3MBTL1 (0.53) | HPGDL3MBTL1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL15861957 | 0.83 | TRPV1 (0.72) | TRPV1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL2021336 | 0.83 | TRPV1 (0.72) | TRPV1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL2021996 | 0.83 | TRPV1 (0.72) | TRPV1HPGDL3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916239-A1 | PYRIDONE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-30 | — | — | EP | disclosed |