SCHEMBL5034532

SCHEMBL5034532

O=C(O)NCCc1ccc(CCO)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.50
CA2 P00918 3/20 0.48
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
KDM4E B2RXH2 1/20 0.48
F13A1 P00488 1/20 0.48
CYP4F2 P78329 1/20 0.48
CYP4A11 Q02928 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
EPHX1 P07099 1/20 0.47
PLAAT5 Q96KN8 2/20 0.46
PLAAT4 Q9UL19 2/20 0.46
PLAAT3 P53816 1/20 0.46
PLAAT2 Q9NWW9 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA1 P00915 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1570160 0.88 CA12 (0.48) L3MBTL1CA2CA12CA9KDM4E
SCHEMBL5031996 0.86 TRPV1 (0.51) L3MBTL1ALDH1A1HPGDPLAAT5PLAAT4
SCHEMBL1437502 0.83 KDM4E (0.69) KDM4EF13A1NPC1RAB9APLAAT5
SCHEMBL4584283 0.83 NPC1 (0.64) CA2CA12CA9KDM4EF13A1
Phenethylcarbamic Acid SCHEMBL249525 0.83 CA12 (0.68) L3MBTL1CA2CA12CA9NPC1
SCHEMBL4582082 0.82 TAAR1 (0.65) L3MBTL1NPC1RAB9AALDH1A1PLAAT5
SCHEMBL6708022 0.82 L3MBTL1 (0.49) L3MBTL1CA2CA12CA9KDM4E
SCHEMBL6540250 0.82 CA12 (0.47) CA2CA12CA9KDM4EF13A1
SCHEMBL4511148 0.82 KDM4E (0.52) CA2CA12CA9KDM4EF13A1
SCHEMBL915701 0.82 ESRRG (0.55) CA2CA12CA9KDM4EF13A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1916239-A1 PYRIDONE COMPOUND BANYU PHARMACEUTICAL CO., LTD. (JP) 2008-04-30 EP disclosed