SCHEMBL5032088

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5032073	0.89	ABCB1 (0.39)	MCL1IKBKETBK1IL2NPC1
	SCHEMBL5029720	0.87	MCL1 (0.40)	MCL1IKBKETBK1IL2TYK2
	SCHEMBL14360826	0.84	TYK2 (0.46)	MCL1IKBKETBK1TYK2NPC1
	SCHEMBL5033875	0.83	MCL1 (0.40)	MCL1IKBKETBK1IL2TYK2
	SCHEMBL5027384	0.83	NPC1 (0.47)	IKBKETBK1TYK2NPC1RAB9A
	SCHEMBL2891693	0.83	TYK2 (0.41)	IKBKETBK1TYK2NPC1RAB9A
	SCHEMBL5029502	0.83	CYP11B2 (0.46)	TYK2NPC1RAB9ANAMPTHTT
	SCHEMBL5030781	0.82	CYP3A4 (0.44)	IKBKETBK1TYK2NPC1RAB9A
	SCHEMBL5030903	0.82	ADORA2A (0.43)	MCL1IKBKETBK1TYK2NPC1
	SCHEMBL5030789	0.81	POLB (0.40)	IKBKETBK1TYK2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.