Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032091 | 1.00 | HDAC1 (0.47) | HDAC1HDAC2DPP8DPP7DPP4 | |
| SCHEMBL16327875 | 0.86 | HDAC1 (0.60) | HDAC1HDAC2DPP8DPP7DPP4 | |
| SCHEMBL10088326 | 0.86 | HDAC1 (0.60) | HDAC1HDAC2DPP8DPP7DPP4 | |
| SCHEMBL16181596 | 0.86 | HDAC1 (0.60) | HDAC1HDAC2DPP8DPP7DPP4 | |
| SCHEMBL30424446 | 0.86 | HDAC1 (0.60) | HDAC1HDAC2DPP8DPP7DPP4 | |
| SCHEMBL4622382 | 0.85 | IDO1 (0.43) | HDAC1HDAC2ECE1IDO1MCHR1 | |
| SCHEMBL5034810 | 0.85 | MMP2 (0.47) | CPB2MCHR1CTSB | |
| SCHEMBL5034811 | 0.85 | MMP2 (0.47) | CPB2MCHR1CTSB | |
| SCHEMBL13411458 | 0.83 | HDAC1 (0.59) | HDAC1HDAC2DPP8DPP7IDO1 | |
| SCHEMBL30480376 | 0.83 | HDAC1 (0.59) | HDAC1HDAC2DPP8DPP7IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144728-A1 | CONJUGATES WHICH BIND A BLOOD PROTEIN SUCH AS HUMAN SERUM ALBUMIN AND METHODS OF USING THE SAME IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO IMAGING S.P.A. (IT) | 2008-11-27 | — | — | WO | disclosed |