SCHEMBL5032103

SCHEMBL5032103

C=CC(=O)OCCCc1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 9/20 0.45
TSHR P16473 4/20 0.44
HPGD P15428 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.42
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
APOBEC3A P31941 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 1/20 0.41
THRA P10827 5/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TP53 P04637 2/20 0.37
HIF1A Q16665 2/20 0.37
HSD17B10 Q99714 1/20 0.37
RARB P10826 1/20 0.37
MET P08581 1/20 0.37
AKR1B10 O60218 1/20 0.37
AKR1B1 P15121 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15726793 1.00 THRB (0.45) THRBTSHRHPGDCTDSP1KDM4E
SCHEMBL21880707 1.00 THRB (0.45) THRBTSHRHPGDCTDSP1KDM4E
SCHEMBL2311466 0.96 THRB (0.47) THRBTSHRHPGDCTDSP1KDM4E
SCHEMBL13839894 0.96 THRB (0.48) THRBTSHRHPGDCTDSP1KDM4E
SCHEMBL1628452 0.96 THRB (0.48) THRBTSHRHPGDCTDSP1KDM4E
SCHEMBL23893940 0.95 THRB (0.41) THRBTSHRHPGDCTDSP1KDM4E
SCHEMBL19229845 0.95 THRB (0.44) THRBTSHRHPGDCTDSP1KDM4E
SCHEMBL2307644 0.95 THRB (0.46) THRBTSHRHPGDCTDSP1KDM4E
SCHEMBL26268121 0.95 THRB (0.46) THRBTSHRHPGDCTDSP1KDM4E
SCHEMBL12454726 0.94 THRB (0.47) THRBTSHRHPGDLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230333494-A1 PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2023-10-19 US disclosed
EP-4246237-A1 PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2023-09-20 EP disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-8383305-B2 Image forming apparatus RICOH COMPANY, LTD. (JP) 2013-02-26 US disclosed
US-20110286777-A1 LUBRICANT AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2011-11-24 US disclosed
US-20110059393-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2011-03-10 US disclosed
US-20110020740-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD (JP) 2011-01-27 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge KDM1A, C9, JMJD6 THRB 4693/4885TSHR 4581/4885HPGD 2767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.