SCHEMBL2307644

SCHEMBL2307644

C=CC(=O)OCCCCCc1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 9/20 0.46
TSHR P16473 2/20 0.45
ALDH1A1 P00352 2/20 0.45
CYP3A4 P08684 1/20 0.45
HPGD P15428 1/20 0.42
THRA P10827 6/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
RARB P10826 6/20 0.39
RARA P10276 1/20 0.39
MAPT P10636 1/20 0.39
MTOR P42345 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.38
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
APOBEC3A P31941 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26268121 1.00 THRB (0.46) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL2311466 0.99 THRB (0.47) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL23937021 0.96 THRB (0.49) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL23937050 0.96 THRB (0.49) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL5032103 0.95 THRB (0.45) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL15726793 0.95 THRB (0.45) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL26268488 0.95 THRB (0.48) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL21880707 0.95 THRB (0.45) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL1630809 0.95 THRB (0.50) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL14588414 0.93 TSHR (0.53) THRBTSHRALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230333494-A1 PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2023-10-19 US disclosed
EP-4246237-A1 PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2023-09-20 EP disclosed
US-11754901-B2 Electrochromic device, wearable device, and method for driving electrochromic device RICOH COMPANY, LTD. (JP) 2023-09-12 US disclosed
US-20170329199-A1 ELECTROCHROMIC DEVICE RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170329198-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-17 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-8383305-B2 Image forming apparatus RICOH COMPANY, LTD. (JP) 2013-02-26 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-20110286777-A1 LUBRICANT AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2011-11-24 US disclosed
EP-2000855-B1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH CO LTD (JP) 2011-08-03 EP disclosed
US-20110059393-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2011-03-10 US disclosed
US-20110020740-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD (JP) 2011-01-27 US disclosed
US-20100330475-A1 IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE BEARING MEMBER RICOH COMPANY LIMITED (JP) 2010-12-30 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-12-11 US disclosed
EP-2000855-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge Ricoh Company, Ltd. (JP) 2008-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge KDM1A, C9, JMJD6 THRB 4693/4885TSHR 4581/4885ALDH1A1 1243/4885
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT TET2, TET1, TET3 THRB 658/4885TSHR 1413/4885ALDH1A1 976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.